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Author Topic: oestradiol level  (Read 4745 times)

dangermouse

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Re: oestradiol level
« Reply #30 on: April 10, 2017, 05:07:43 AM »

There are two schools of thought re what causes PMT but if it gets progressively worse from age 35 up to menopause it's likely to be too low progesterone.

Both oestrogen and progesterone start falling over the last week of the cycle (although graphs suggest prog comes down first but I'm not sure how accurate they are!). However, our own progesterone starts declining from about age 35, where oestrogen stays high until just before the menopause (52 average) when it completely nose dives and causes (I presume) the hot flushes, dryness and the more classic meno symptoms.

Oestrogen can go very high in the second half of the cycle but progesterone opposes it and keeps it from surging too much. However, if PMT was worse when in 20s and lasted for the whole 2nd half of the cycle then it could be the progesterone intolerance issue your mention. Although that should get better from 30s as prog starts falling.
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