I took Tibilone for 15 years and felt great, no side effects ever, nothing. However when I reached 70 last year, my doctor accepted that I wanted to stay on HRT but said he would like me to change to Elleste. After 3 months I began to bleed, had a clear scan. Four months later I had two successive bleeds that felt like full blown periods. This led to my having a clutch of tests including a biopsy. All clear again, thank goodness. The hospital consultant was very supportive and recommended me taking Tibilone again. So I'm back on it and feeling very good and positive about it; I just could have done without all those tests! Tibilone is great as far as I am concerned.