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Menopause Matters magazine ISSUE 81 out now. (Autumn issue, September 2025)

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Author Topic: Idiots Guide To Tibolone  (Read 8965 times)

Murphydurf

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Idiots Guide To Tibolone
« on: February 05, 2017, 09:48:06 AM »

I wonder if one of the Tibolone girls could give us a simple, how it works/what's in it/safety comparison to BHRT guide to Tibolone.

I'm sure there's lots of ladies, myself included who'd like that info in a simple straightforward format. Apologies if it's already been done.

Mx
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Annie0710

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Re: Idiots Guide To Tibolone
« Reply #1 on: February 05, 2017, 10:01:56 AM »

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671819/


I'm useless at explaining this, I'm still trying to get my head round it all but it seems it's a synthetic that mimics or alerts our receptors to give the benefits of oestrogen, progesterone and testosterone

I've also heard the word steroid used x
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Tempest

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Re: Idiots Guide To Tibolone
« Reply #2 on: February 05, 2017, 10:02:58 AM »

Indeed, Murph!

It's a drug called a STEAR, which is different to other HRT's. It's effectively a steroid which is broken down into components that have weak estrogenic, progestogenic and Testosteronergic properties. It's a very old drug, with a long proven track record. It preserves bone and is not shown to raise the risk of DVT. It doesn't increase the density of breast tissue and is not known to increase risk of breast cancer. It should be taken post menopausally or after TAH/BSO. It has potential to improve libido due to Testosteronergic effect. It's shown to improve vaginal secretions more favourably than other HRT's, thus helping with VA. It's the only licenced HRT to include Testosteronergic properties. My GP has ladies who are still on it over the age of 60 - after this age, there is a slight raise in stroke risk but ok to stay on it if monitored by GP and patient is aware of risk.

Dose is 2.5mg daily, in tablet form and can be taken any time to suit with or without food.

Side effects are minimal - from the ladie's experiences on here it tends to be joint pain at first and some dizziness with some insomnia which seems to settle with time. Mood can be a bit wacky for the first few weeks, but nothing major - it's just the drug settling in.

I hope this helps! xxxxx
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Murphydurf

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Re: Idiots Guide To Tibolone
« Reply #3 on: February 05, 2017, 10:07:30 AM »

Brilliant Tempest - sounds amazing! Why aren't we all prescribed this? Is it pharma issues again?

Mxx
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Tempest

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Re: Idiots Guide To Tibolone
« Reply #4 on: February 05, 2017, 10:10:13 AM »

It's because bio identical transdermals are now the 'preferred choice', even if the blasted things don't work........ >:( >:( >:(
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Murphydurf

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Re: Idiots Guide To Tibolone
« Reply #5 on: February 05, 2017, 10:11:00 AM »

I'm going to have a chat with GP about Tibolone.

Mx
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Tempest

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Re: Idiots Guide To Tibolone
« Reply #6 on: February 05, 2017, 10:16:57 AM »

Good thinking, Murph! As I always say, HRT should fit US and our needs - we shouldn't have to struggle on endlessly with a type/delivery that doesn't work for us just because it's the 'in thing'. xxxx
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walking the dog

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Re: Idiots Guide To Tibolone
« Reply #7 on: February 05, 2017, 10:17:47 AM »

Fab thread murphydurf and great idea
I shall most likely be joining the tibolone crew soon 😊
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Annie0710

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Re: Idiots Guide To Tibolone
« Reply #8 on: February 05, 2017, 10:19:02 AM »

Oh Tempest you are great at explaining things !

I can really vouch for the benefits for VA.  I haven't used Sylk externally for a couple of weeks now with no problems, the only reason I haven't used it is because I've had NO soreness to remind me.  I'm actually forgetting some of my vagifem doses too because of the same reason and I'm lubricated
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Murphydurf

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Re: Idiots Guide To Tibolone
« Reply #9 on: February 05, 2017, 10:19:25 AM »

It just sounds too good to be true -ie it could provide all the missing elements and be slightly less harmful than standard hrt? Is that the case?

Mx
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Annie0710

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Re: Idiots Guide To Tibolone
« Reply #10 on: February 05, 2017, 10:24:41 AM »

What drew me to it was that it provides all 3 hormones, provide the wrong word but what Tempest said lol

Something's seriously been missing for me during meno and T gel just wasn't doing what others were saying it was doing for them

I've still got things I'd like to improve, this social anxiety is the biggest (sorry I go on about it so much but it's really near wrecked my world a lot of the time) but this weekend being away with work has shown me I've made some improvement

To be honest if dog muck was the answer I'd try it ! X
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Tempest

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Re: Idiots Guide To Tibolone
« Reply #11 on: February 05, 2017, 10:25:00 AM »

I saw a study (I'll find the link, as I know some members like proof) that in conclusion, the researchers said it came very close to being 'the perfect HRT'. This was the exact words used......

For this reason, I'm going to give it a good trial. If this doesn't work, then I'm throwing in the towel as NOTHING will for me!

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Murphydurf

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Re: Idiots Guide To Tibolone
« Reply #12 on: February 05, 2017, 10:36:14 AM »

Annie0710 - sounds like it's doing the job for you! Great news, I remember you talking about T and not getting results, I hope it continues to keep doing good things for you. It's such a good feeling to finally say goodbye to the person you didn't want to be and continue to feel better.

Tempest - I'd be really interested so see that research if you can find it.

Mxx
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Murphydurf

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Re: Idiots Guide To Tibolone
« Reply #13 on: February 05, 2017, 10:37:57 AM »

Just to be clear - you don't need additional prog or to have a bleed? I still have all lady bits.

Mxx
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Annie0710

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Re: Idiots Guide To Tibolone
« Reply #14 on: February 05, 2017, 11:04:33 AM »

No apparently Tibolone covers everything apart from VA sometimes x
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