Hi, ladies!
As you know, I'm trialling Tibolone and so far it's been pretty difficult. I have particularly been having problems with mood and also suffer from CPTSD. My psychiatrist has suggested Quetiapine previously and if I don't see significant improvement on the Tibolone to warrant continuing, I will then pursue this avenue (in my case, then possibly adding in ERT once my mood has stabilised for bone/heart protection).
I have been researching clinical data on Quetiapine and I wanted to share this study with you as it showed good results for postmenopausal mood and vasomotor symptoms, as well as quality and quantity of sleep:
http://www.europsy-journal.com/article/S0924-9338(09)70913-7/abstractThis might be very useful to you ladies who cannot use HRT - it has antidepressant effects but it's primary function is as a mood stabiliser.
Many studies have also shown that estrogen replacement post menopause does not have a significant effect in improving mood specifically other than the 'knock on effect' possibly from alleviating vasomotor symptoms and sleeplessness (whereas it seems to have a more positive effect in perimenopause if there are no other contributing factors for low/unstable mood), so this is worth considering if low mood/anxiety/mood instability is a major concern for you.
I hope you find this interesting! xxxxxx