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Author Topic: Opinions Required.  (Read 6335 times)

Kathleen

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Opinions Required.
« on: August 14, 2016, 10:00:47 AM »

Hello ladies.

I would like to have your opinions please as I have a decision to make very soon.

 I am nearly sixty and had my last period six years ago, I had a variety of symptoms but didn't begin HRT until three years ago. I am currently using Evorel Conti 50 mcg patch but I still have flushing every day plus anxiety and low mood, I recently had my oestrogen levels tested and was told they are 'sub optimal' at 94 pmol/L. I now need to see my GP to discuss the results and decide what action to take.

 If I were younger I would gladly increase my HRT and raise my oestrogen levels as that is evidently what I am lacking but something is holding me back. Part of me thinks that at my age I should try to adapt to low oestrogen and find a way to tolerate my symptoms whilst also hoping that very soon I'll begin to feel better and all the flushing etc will fade away as I become older. I have friends who are not using HRT and I sometimes think they are coping better than I am! I know many of us are pressured into coming off HRT at sixty and that is a concern of mine but  ideally I'd like to feel 'normal' without raising my oestrogen levels.

Can I ask  how you would resolve this dilemma?  Did any of you older ladies  think that this whole business should be over soon and be tempted to stick it out, and if you believed HRT was still necessary how did you arrive at that decision?

Sorry if this is an odd question but it's been bothering me for some time and I can't decide what to do for the best.

Thanks for reading and wishing you all well.

K.
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babyjane

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Re: Opinions Required.
« Reply #1 on: August 14, 2016, 10:56:00 AM »

hello Kathleen, I can't answer the question you ask because I have never used systemic HRT, only Vagifem for VA.  However 5-6 years ago hot flushes began as did unpredictable mood swings, loss of confidence and anxiety kicked in about 2 years ago. I am 59 now.  Personally I chose to deal with the symptoms as they arose which gave me a degree of control and I was fortunate in that my symptoms were never debilitating and I did not have bleeding.

I have noticed this year that my flushes have been dwindling, are milder and I don't get them every day.  My mood is more stable but I have been having psychotherapy for childhood trauma and as that is worked through I find I am in a better place emotionally.

I do believe that the menopause does work itself out but it is an individual thing how we cope with it whilst it does and there are also many ladies who have a much worse time than I did, especially if they have bleeding and still go out to work.

I don't know much about HRT but plenty of ladies here do, however I think I have read on this forum that 60 is no longer a definitive cut off point for coming off HRT and there definitely is no 'should' about it.
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Ju Ju

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Re: Opinions Required.
« Reply #2 on: August 14, 2016, 12:48:39 PM »

No 60 is no longer a cut off point. I started HRT at age 60. I was not suffering from the normal symptoms enough to warrant HRT, apart from extreme exhaustion and insomnia, which had a huge impact on the quality of my life. I was told by several medics I should consider CFS as a diagnosis. I sought advice from a private gynaecologist, recommended by my GP. I couldn't believe the difference. I have my life back, though I do have to pace myself and I would not cope with working. There are risks, but I weighed up quality versus quantity of life. Many of my relatives have lived to a great age and the thought of carrying on like I was, was unthinkable if there was an alternative.

It is very individual. I know of people who cope perfectly well without HRT and others, where the risks would be too great a concern. There is no right or wrong decision. It is so personal a decision.
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Evelyn63

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Re: Opinions Required.
« Reply #3 on: August 14, 2016, 01:43:03 PM »

hello kathleen, my story is similar to that of Babyjane , though I am older at 63, ( just hanging on by a thread )  I had just started on HRT in 2002  when the " scare" became big news and I suppose like lots of other women I made the decision to stop taking it.  I seem to have weathered the storm, and never get hot flushes now though to be honest the ones I did experience werent too bad so I consider myself lucky in that respect. I still get warm though , and sweaty at times but nothing that a light duvet and one leg hanging out cant fix.  The mental/emotional side of things were to me the worst bit of the whole thing, and I was on AD"s for a short while after my mother and mother in law died, that was seven years ago, I only took them for a short period and since that Im fortunate to be able to manage my mood ok.   I do still have occasional episodes where Im inclined to catastrophise every day situations, but Ive learnt to try and deal with those . 

I have just recently commenced Vagifem, its a bit early to tell if its made a dramatic difference, I was prescribed it for VA and to see if it would help with the recurrent UTI"s and cystitis that I have suffered from . 

I am sure some other ladies will be able to assist you and give you more relevant information.  One thing Ive clung on to , is that to all intents and purposes I seem to have at last come out the other side, though it took me a long time ! 
« Last Edit: August 14, 2016, 01:45:29 PM by Evelyn63 »
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vickypk

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Re: Opinions Required.
« Reply #4 on: August 14, 2016, 02:45:11 PM »

Hi Kathleen  I'm similar to you on Everol conti.  I've been using the patches for a year, I am a lot better than I was.  The headaches, anxiety, flushes and VA have greatly improved.  I still have low mood sometimes.  I don't know what to do next really.  I have tried the oestrogel and utrogestan regime but had so many side effects with that, felt worse after three months of using that.  I am not sure whether to try something else or stick with the Everol patches. Hope you are okay and let me know how you get on. 
best wishes
xx
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CLKD

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Re: Opinions Required.
« Reply #5 on: August 14, 2016, 03:51:58 PM »

I haven't read the responses [too tired] but I usually say "If you are hungry, do you not eat?  If you have pain, do you not take relief?"  so if your body needs HRT, why stop …… age is a number.  Meno symptoms can make ladies feel 90 when they are 50+.  Why suffer, the medication is there!

GPs should advise patients about any possible risks and leave the patient informed so that they can make decisions, this should be as true of HRT as any other speciality.

I have to take ADs for Life.  It took time to accept that my brain needs support but now that Himself and I have a Life together, I feel enabled.  Not every day but at least I get out of bed ;-).

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linz57

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Re: Opinions Required.
« Reply #6 on: August 14, 2016, 07:41:08 PM »

I'm in the same situation as you  Kathleen and it is a dilemma. I too started hrt relatively late and don't really want to increase my dosage, yet don't want to keep feeling as I do now . If we have low doses of estrogen to keep things ticking over we won't feel as well as we probably will if we increase, but if you're like me , you will worry about the dangers of higher doses. It's such a difficult decision.
I've recently cut my conti patch in half and so far the hot flushes aren't too severe but my emotions are all over the place and I keep bursting into tears. Is it worth this? I'm off to discuss a new regime with my doc tomorrow but still I don't know what to do regarding dosage. Can we ride this out? I just don't know😢
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CLKD

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Re: Opinions Required.
« Reply #7 on: August 14, 2016, 07:48:04 PM »

If you are hungry after eating what do you do linz57?  Do you moan about feeling hungry or do you have a snack  :-\ ….  how long have you been on the current regime and what do you really expect if you keep cutting the patch in half: by doing so do you get the same absorption ………. what dangers exactly do you think will happen ????? who has told you about dangers anyway!!!

The danger is more likely to affect your heart and bones if you don't have *enough* oestrogen  :sigh: - a lady needs at least 4-6 months of HRT to allow the body to adjust, unless side-effects are truly awful then why change regime? 

Of course you can 'ride it out' but are you prepared to put up with feeling ill all the while?  I know from taking ADs - which I fought against for years - I feel well again, I NEVER want to feel as ill as I did when depression took hold  :'(

HRT isn't a cure but if it relieves symptoms and yes, it can be Trial and Error but the drug needs to be given time.
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linz57

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Re: Opinions Required.
« Reply #8 on: August 14, 2016, 08:00:21 PM »

I've only been on half patch for just under a month and I know this sounds ridiculous , but I did this because the full patch wasn't cutting it anymore. Yes, I know how daft that sounds, especially when a higher dose would probably have helped, but my weird logic told me if 50mcg left me feeling crap then I may as well feel the same on a lower dose. Hmmm, yes, as I said, mad!
I suppose my fears as I'm getting older are blood clots and weight gain as I've put on two stone since being on this patch (18months
Yes, my logic is warped😁
I am off to change to another regime tomorrow as the 50mcg patch wasn't keeping my endo lining thin enough .
« Last Edit: August 14, 2016, 08:03:27 PM by linz57 »
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Hurdity

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Re: Opinions Required.
« Reply #9 on: August 14, 2016, 08:13:48 PM »


Can I ask  how you would resolve this dilemma?  Did any of you older ladies  think that this whole business should be over soon and be tempted to stick it out, and if you believed HRT was still necessary how did you arrive at that decision?


Kathleen I know exactly how you feel - well almost! The dilemma part anyway. The difference between you and me apart from a few years in age (I am 63) is that the same dose of oestrogen stopped all my flushes and sweats from very soon after I started HRT (in late peri-menopause at age just under 54) - and they have stayed away. Also last time I had my oestrogen levels measured they were 200 and something pmol/l - so this explains the difference - even though we all have different optimal levels to banish symptoms and to feel good.

The other difference of course - which we have discussed before is that you are not only on continuous combined HRT but also taking a synthetic progestogen - which although it is not known to impact on actual oestrogen levels - may well attenuate oestrogen's beneficial effects to some extent - notably flushes and sweats (although your  sub-optimal oestrogen levels speak for themselves).

Women talk about being through the menopause and symptoms working themselves out - but it is a truism that oestrogen deficiency lasts forever as we have discussed many times. The vaso-motor symptoms (of flushes and sweats) may or may not diminish at some point after withdrawal from HRT, but any long term health consequences of oestrogen deficiency may become more apparent and have an effect on your health. However you cannot take away the beneficial years you have had while on HRT so - it could be that you have already delayed any negative effects until much further down the line!

The dilemma is really only a problem for those of us who still have a womb (discounting other specific factors which might affect why women might choose to stop HRT) - because we have to decide - in your case whether to go on taking cotninuous combined HRT long term - and that is with the progestogen, or in mine and several others of us in our 60's - how long we are prepared to continue having a withdrawal bleed though cyclical HRT.

If you've had a hysterectomy - the decision is pretty straightforward provided you are generally healthy and don't have any other risk factors.

I am wondering exactly the same - when do I stop? When do I start to reduce? What will I feel like? How will I cope? How long before I feel anything like normal again? In my case I introduced testosterone into the mix - due to incredible tiredness, and muscle aches and pains after exercise - and I don't want to be condemned to a life of pains and exhaustion or a diagnosis of CFS or similar - as Ju Ju was threatened with - if these symptoms return. I don't want to lie on a sofa not exercising and mopping my brow!

I don't see why you should not try a slight increase in HRT - or at least perhaps try a cycle. I know you tried a different type for a while (estrogel? - but didn't get on with it?) - but I would strongly recommend changing to Estradot 50 mcg - the same dose as Evorel and perhaps Utrogestan. Could you bear to go back to a cycle - perhaps a longer cycle - and have a bleed? It's really not that bad and worth it not to have to take progesterone all the time. I actually slightly increased mine recently - only because I didn't want to become testosterone dominant (androgenic side effects) so I've added 12.5 mcg to my dose (by judicious snipping of patch!).

It also depends on your work situation - as you won't be at retirement age for a while? I still work part-time and there is no way I could countenance the lying about brow mopping lark!!! I need to use lots of energy in my work when I am out so have to be on top form.

You are still young (in my eyes) so changing or increasing slightly cannot do you any harm if you are otherwise healthy, fit, good shape and don't have other health problems - well at least the risks are lower than other lifestyle factors - being overweight, smoking, drinking too much alcohol, poor diet etc.

I haven't decided yet what/when to reduce and how to do this along with the testosterone - (without becoming too hairy  ;D ).

linz57 - I can't remember how old you are (?57) but if you've only recently started HRT and it hasn't stopped the symptoms then definitely increase the dose - I mean there is no point taking it if you are still suffering. The idea is to improve quality of life. 50 mcg is not a high dose anyway - it is the standard medium dose for post-menopausal women (as you can see from the conti patch doses) - especially I imagine those who went through menopause at or beyond the average menopausal age.

Just a few thoughts and a bit of a ramble but hope some of it is helpful. I don't really have any answers - but I do think it is important to feel well now - rather than worry too much about the future. It's not as if you are on 3 or 4 pumps of gel with oestrogen levels at 500 pmol/l or more.  This would be difficult both to maintain and to reduce from I imagine, if you still have a uterus.

Hurdity x
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CLKD

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Re: Opinions Required.
« Reply #10 on: August 14, 2016, 08:17:36 PM »

Aaahhh  -  have you had a womb scan, meno-brain can't remember  ::)

What makes you think that you would suffer blood clots?  I haven't put on weight but my shape has altered due to loss of oestrogen causing laxity of muscles = drop of apron  >:(.  So I look fat in different places by the end of the day!

Let us know how you get on and what the GP suggests.

Why stop if HRT is helping  :-\ ….. do you spend the whole day worrying about take/not what the GP prescribes, maybe think back to why you went to the Surgery initially and what you expected to achieve???? HReplacementT does what it says on the tin  :-\ ……… if you had other chronic conditions, i.e. diabetes, would you consider stopping medication?  ???
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linz57

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Re: Opinions Required.
« Reply #11 on: August 14, 2016, 08:28:02 PM »

Yes I've had scans and a hysteroscopy recently, but I'm thinking if a 50 mg conti patch isn't keeping my endo lining thin enough then will a 75 mg also keep it slightly thickened?
Earlier today I posted elsewhere on here about changing and I received good advice about either changing to a sequi regime or having a Mirena coil and an estrogen patch. With the Mirena I could adjust the estrogen doses to suit.
Why the worry about clots? Oh, my grandad died of a blood clot and I visited him in hospital before he died. It just put the fear into me I suppose.
There is no definite answer regarding when we should reduce doses, but the wondering and thinking does sometimes make us feel like we are trying ourselves in knots. I think this is the problem, there are no laid down hard and fast rules, it's all trial and error.
I'm 59 in October Hurdity, I sailed through peri feeling absolutely fantastic,  but since being post meno the you know what has really hit the fan

Kathleen, how bad are your symptoms on a daily basis? Reading this thread is making me thing again about dosage. Do we really  want to keep feeling rotten when help us at hand?  Oh it is so difficult.....
« Last Edit: August 14, 2016, 08:34:43 PM by linz57 »
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CLKD

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Re: Opinions Required.
« Reply #12 on: August 14, 2016, 08:32:48 PM »

There are guidelines though and one is to keep to a maintenance dose for at least 3 cycles.  :sigh:  After that an increase or decrease or a change of HRT may be required.  But the body needs to adjust to what we put into it.

What caused your Grandad's blood clots?  Something you can ask your GP about if that is what is making you doubt HRT as a aid through your hormonal changes. 

I've probably asked: and you have problaby told me  ::) but do you keep a symptom/mood/food/medication diary?  I jot down when my anxiety becomes awful and if I go to the loo 'cos I simply can't remember  >:( ………..

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linz57

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Re: Opinions Required.
« Reply #13 on: August 14, 2016, 08:42:22 PM »

No I haven't kept a diary, maybe I should then I may see a pattern emerging. My anxiety is generally not too much of a problem, it's when I start having medical problems....and being post meno there's always something cropping up,......that it kicks in.
I've been like a shreiking shrew this last two weeks, along with constantly bursting into tears so I guess I really do need to up the dose of estrogen and take one day at a time instead of thinking long term.
I don't know what caused the clots , he was on warfarin though.
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Taz2

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Re: Opinions Required.
« Reply #14 on: August 15, 2016, 06:41:21 AM »

Linz57 - there is a clotting factor test which your GP can carry out to check if you have inherited any of the faulty clotting genes but I believe you may have to have had more than one family member affected. It doesn't check for all of them but the most common ones can be ruled out.

The problem with continuing with HRT over 60 is seen to be in the increased risk of heart attack and stroke rather than cancer but, as has been said on here many times, it is the quality of life which has to be taken into account. I think that somewhere I found that under the age of 60 the benefits of HRT outweigh the risk, between 60 and 70 then the risks and benefits are the same and after 70 the risks outweigh the benefits but I'm not sure where the info was on this now.

Taz x
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