Justjules, I think I know how you feel. My "anxiety" was so bad months ago they my legs felt like they wouldn't hold me. Sometimes standing in the shower was a chore. I trembled constantly. I could walk or I could lie down, but sitting still or standing still was nearly impossible. I was convinced that I had something else neurological going on. Added estrogen has helped most of the physical manifestations of my "anxiety" but mentally I'm still often wrecked. I'm not so weak and trembling as I was, now I'm only hyper-emotional. And it switches on out of nowhere. I've tried to pay attention to triggers. Sure, being nervous or stressed about something can do it, but often times I wake in the morning with no plans to do anything but work and play around the house and the unsettled feeling is there. It's very uncomfortable. Then I think about how miserable it feels and wonder of it will ever subside so I can be normal again and I melt into tears. I have read about the not giving into it idea that changing plans only reinforces it, but I'm not sure I buy that. I do what I'm comfortable doing when I feel I will succeed. Last week I tried to push beyond my comfort level. I already knew I was having a nervy day, but tried to ignore it and push on. I failed miserably, and I think that failure set me back more than bailing out to begin with would have. I am doing more now than I had been doing. I'm doing everything I possibly can. It just happens that a lot of things are impossible for me right now. I am sick and tired of this, and I don't know what you should do, other than as CLKD says, do what feels right to you. My husband has been very supportive. He's doing everything for my family now and not complaining. But I still feel the pressure to get back to the routine and carry my weight. I asked him if he could help me take the kids to the doctor appointment that I had to reschedule from my failed attempt last week. He didn't tell me that I need to get myself together. He stated the fact that he is very busy at work this week but he would try. It was pure, nonjudgmental fact, but I took it as extreme pressure to get my act together. Although it helps to have a supportive husband, unless he can turn this mental stuff around, all the support in the world doesn't relieve the pressure we put on ourselves. I'm not saying you're putting too much pressure on yourself. I know I am not aspiring to end world hunger or anything, I would just like to be able to hop in the car and run to the park on a nice day without giving it a second thought. I am avoiding the ADs as long as I can, because I see where so many women have trouble adjusting to them and getting the right ones, and later coming off of them, just like hrt. To me it seems like yet another set of levels and dosages to contend with. I will try them eventually if in time this doesn't work out. What CLKD said about the other hormones, I have my thyroid levels tested, and I plan to ask about cortisol. Part of my hesitancy about the ADs is that they don't test anything to determine that physiologically I need an AD. They can test my sex hormones, thyroid, adrenals, vitamin D, etc but the ADs feels like a stab in the dark for the ADs. Anyhow, I'm rambling but wanted to give you a little support and let you know you're not alone.