Coldethyl, checked on a couple of other health forums and it seems that Sertraline is a particular bad one for side affects but they all say stick on it and once the first two weeks are over, things might ease but some have taken up to five weeks, it all seems to vary person to person. I think I am just frightened of what these drugs are doing and how safe they are to take, as I never felt like this with Citalopram. I have also read that it is far better to start on the tiny dose and work up rather than go straight in on the 50mg dose. It makes sense that if you have to slowly wean off these drugs, then surely you should slowly introduce them into your system? I've had anxiety spells for years and this is the worst I think I have felt for a long time. I just hope I can still have the diazepam as it seems that most drs give them alongside Sertraline because they know how bad the start up symptoms are. I don't think I could carry on with them if I didn't have the back up of an occasional diazepam. I will obviously be speaking to Dr next week so will go from there.