Shaz67 and any other ladies who can help. I'm going through this irregular periods now but my main problem is my sore breasts. Well, it switches from left boob to right. My right boob has always been more active to hormone ups and downs as this was the breast that I fed all my babies from the most so it is bigger. Now since being in the change certain times of the month the nipple is really sore and then other times of the month it is the side of my boob. I just feel like i am sore for the majority of the month and it is really making me depressed. My periods are all over the place and as much as i am trying to track when the boobs are sore, it's impossible now as I never know where a period starts and end as they are short, long, heavy, light, it's a nightmare. My last bloodtest said my estrogen level was low, yet everything I read says sore boobs are due to high levels of estrogen... please help if you have been through this.