Hi Goosieloosie. I have been on almost the same, with the 50 patch but 200 utro 10 days per month orally. I also bled a little early on the utro every time. I initially tried changing the timing of the start of utro to 15 days from the start of the bleed, to attempt lining up what could have been my own background cycle with the utro timing. It didn't work, still bled early, but my doctor assured me that bleeding early was not a problem, to complete the course and carry on. I stretched my cycle to 6-7 weeks some last summer to accomodate travels, and felt much better during that time. Because I only take it 10 days and couldn't make myself take it longer due to mood effects, I went back to every 4 weeks at the end of summer. I felt off in November, and hit bottom again in December. Like you, the migraines and low mood seemed to become progressively worse with time. In January I discussed with my doctor and attempted to lower to 100 continuously and about 10 days in began a bleed. I allowed a withdrawal with no utro for 5 days and began utro again at 100. Only a few days in, migraine and frightening depression. I have decided to quit the whole lot. I stopped the utro, and 2 days later, for the first time ever, began a bled after stopping utro, even though I had just finished a bleed a week before. I'm tapering the patch down now and expect I'll to have to go one more course of utro. I know this doesn't help you, but you're experience sounds so similar to mine I thought I sold share.