When using progesterone cream they say don't keep putting it on the same place everyday but when my breasts were painful I just rubbed a small pea-sized amount twice a day where it was painful ie mostly a lumpy area on the right side. Although I did vary the places as well ie inside of wrists, inside of thighs, chest, (and back of neck, where I've been having a painful neck!)
My breast pain has now settled and I used the cream for about 21 days, have had a seven day break and am now going to start using it again for another 21 days to see if this prevents my breast pain.
Its really strange because the cream seems to have given me a boost in well being, in addition to sorting out pain. I have read you shouldn't use too much cream as this can sometimes be unhelpful but it is something you can stop using at any time if necessary.
I know everyone if different and our hormone levels vary at different times but for me this seems to have had a positive effect so far but I am still experimenting.