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Author Topic: Estradiol gel and progesterone tablet advice please? x  (Read 30050 times)

Gig

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #15 on: March 20, 2013, 10:16:31 PM »

Are you talking about 10 days EACH month?

I take norethsterone for 10 days every 8 weeks- was every 12 weeks.  I have read on Prof John Studd's website that 7 days progestins is okay for women who find they are intoelrant.
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Cassie

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #16 on: March 21, 2013, 04:30:52 AM »

Yes 10 days per month should do you just fine vaginally or orally if you prefer, just find that the V route causes less side effects apart from a bit of cramping towards day 5 or so. I would love to be able to take it as I used to 10 days every 12 weeks 100mg but I was getting breakthrough bleeding so he upped it to 200mg monthly.

Good luck
x
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Butterfly22

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #17 on: March 21, 2013, 09:01:33 AM »

Hi ladies,
yes its the 1st to the 10th of each month i take it. x x
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Gig

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #18 on: March 21, 2013, 09:26:35 AM »

Stella

I don't think Studd is unusual TBH- and I have read more widely.

I think that 7 days would be fine TBH.  I take 10 days every 8 weeks as i said, and it was every 12 weeks until the bleeds got a bit too heavy- been doing this for 4 years now under guidance of gynae.  he also said that even 7-8 days worth every long cycle would be okay- as long as you have a bleed , which is the important thing.

When HRT was first prescribed decades ago and it was oestrogen only in the main, that's when the problems arose, but now the pendulum has swung the other way- perhaps a bit too much with too much emphasis on having very regular bleeds coupled with high doses of progestins.

My gynae says that because there is evidence now of the progestin-breast cancer risk ( compared to no higher risk with just oestrogen alone)  that there is some logic in keeping progestins to the minimum and even going oestrogen-only with regular check ups, though this treatment is not allowed under current prescribing licence.

« Last Edit: March 21, 2013, 09:28:53 AM by Gig »
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Butterfly22

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #19 on: March 21, 2013, 10:48:24 AM »

I feel so positive thanks to you ladies, i wish id know about this mix a couple of years ago, i hated the other gel and did want this one originally but my doctor was not so helpful.
Fingers crossed im on the up and also may get some energy back :) x x x
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Hurdity

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #20 on: March 21, 2013, 11:14:25 AM »

Hi there

Haven't time to respond in detail - but Gig - it is important for everyone involved in all of this to know that norethisterone is the most powerful progestogen that is used and cannot possibly be compared with utrogestan. Norethisterone is used to treat endometrial hyperplasia (where the womb lining has over thickened). It is very irresponsible to suggest that 7 days of any progestogen is definitely OK based on your specific prescription with your private gynae. As Stellajane says it's fine for Studd to recommend this - because all his patients are private and will be having scans. In fact I did read on his website ( unless he has changed it) that he only recommended 7 days with annual endometrial scans.

The research anyway is pointing to bio-identical progs like utrogestan is likely to be associated with less risk than the synthetics. Personally I would never use them long term.

All these amounts and days have been worked out based on some research back in 1990's and earlier where there were studies done looking into the incidence of endometrial hyperplasia with different amounts and time length of progestogen.

I agree that the amounts of prog prescribed may be more than necessary for individuals and are designed as a one-size fits all. Also that lower amounts of progesterone are needed when used vaginally. However if you are not intolerant of the progesterone there is no reason not to use what the gynae prescribes and especially for most of us on NHS and can't go and have regular scans.

I use 200 mg vaginally every two months - I reckoned that this would be OK as I said above you need less vaginally than orally. It's more prog than I would like and would rather have an annual scan as I have lengthened my cycle but I keep an eye on symptoms and bleeding etc

I agree lila - the 100 mg monthly for 10 days will hopefully be fine either orally but definitely will be OK vaginally - in fact the usual prescription for monthly utro orally is 200 mg so you will be using less.

My bleed comes about 3 days after stopping the Utro. Just coming to the end of a course at the mo' and effect I have a migraine and feeling rubbish ( it has this effect on me sometimes but usually on stopping it) - but that;s probably because 200 mg vag is a high dose so eventually lots of it gets through... yes have to use a pantyliner at night but that's no big deal (as women - we are used to mess!)

Sorry if this is garbled lila as I am working as well as cotton wool head but just wanted to answer.

Hope it all works for you - just give it time.....

Hirdity x

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Gig

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #21 on: March 21, 2013, 11:53:13 AM »

I am not being 'irresponsible' - it was an opinion, just like most posters. What anyone does is entirely up to them- my comments were based on what I have been advised, albeit with a differnt progestin. You will find there is a difference of opinion/ treatment between even gynaes and what is written on a website by one may not always equate to what they do in practice. I don't have annual scans- but I do have investigations if there is a need. (Studd is not my dr by the way.)

 I was not suggesting any poster does what I say- it's between them and their doctor.  I was expressing an opinion- not telling them to go ahead and take only 7 days.

« Last Edit: March 21, 2013, 12:22:34 PM by Gig »
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Butterfly22

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #22 on: March 21, 2013, 05:13:43 PM »

Hi there

Haven't time to respond in detail - but Gig - it is important for everyone involved in all of this to know that norethisterone is the most powerful progestogen that is used and cannot possibly be compared with utrogestan. Norethisterone is used to treat endometrial hyperplasia (where the womb lining has over thickened). It is very irresponsible to suggest that 7 days of any progestogen is definitely OK based on your specific prescription with your private gynae. As Stellajane says it's fine for Studd to recommend this - because all his patients are private and will be having scans. In fact I did read on his website ( unless he has changed it) that he only recommended 7 days with annual endometrial scans.

The research anyway is pointing to bio-identical progs like utrogestan is likely to be associated with less risk than the synthetics. Personally I would never use them long term.

All these amounts and days have been worked out based on some research back in 1990's and earlier where there were studies done looking into the incidence of endometrial hyperplasia with different amounts and time length of progestogen.

I agree that the amounts of prog prescribed may be more than necessary for individuals and are designed as a one-size fits all. Also that lower amounts of progesterone are needed when used vaginally. However if you are not intolerant of the progesterone there is no reason not to use what the gynae prescribes and especially for most of us on NHS and can't go and have regular scans.

I use 200 mg vaginally every two months - I reckoned that this would be OK as I said above you need less vaginally than orally. It's more prog than I would like and would rather have an annual scan as I have lengthened my cycle but I keep an eye on symptoms and bleeding etc

I agree lila - the 100 mg monthly for 10 days will hopefully be fine either orally but definitely will be OK vaginally - in fact the usual prescription for monthly utro orally is 200 mg so you will be using less.

My bleed comes about 3 days after stopping the Utro. Just coming to the end of a course at the mo' and effect I have a migraine and feeling rubbish ( it has this effect on me sometimes but usually on stopping it) - but that;s probably because 200 mg vag is a high dose so eventually lots of it gets through... yes have to use a pantyliner at night but that's no big deal (as women - we are used to mess!)

Sorry if this is garbled lila as I am working as well as cotton wool head but just wanted to answer.

Hope it all works for you - just give it time.....

Hirdity x

Hi Hurdity,
Just realised you have helped me in the past also so thankyou for taking the time, its much appreciated.
I will do the 10 days oral and see how i go but i will more then probely end up doing the other way as my ME makes me so sensitive to chemicals, but im so pleased i have something that may be suited so thankyou :) x x x
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Hurdity

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #23 on: March 25, 2013, 06:42:51 PM »

I was not suggesting any poster does what I say- it's between them and their doctor.  I was expressing an opinion- not telling them to go ahead and take only 7 days.
Sorry Gig it didn't quite come over as I intended. Was feeling rubbish Weds- Fri with hormonal migraine and also trying to work and in a hurry. I usually read through before posting but didn't then. The rest of my post stands as I meant though! Yes I know Studd isn't your doc. I think he prescribes similar to your doc though and sometimes offers norethisterone for 7 days. No offence meant.
Hurdity x
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Gig

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #24 on: March 25, 2013, 07:08:45 PM »

No problem! No offence taken- forums are notorious for writing something in a hurry then thinking afterwards!
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Butterfly22

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #25 on: April 15, 2013, 07:46:52 AM »

Hi Ladies, hope you all had a nice Easter,
Ive stareted the gel almost two months ago and started the ustrogen tablet on the 1st to 10th this month but no period!
Is this right?
Ive banging head, light cramp and bloated, feel like im going to get one but not!
Any advice be great thanks x
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meno lesley

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #26 on: April 15, 2013, 08:47:46 AM »

Hi

I've been taking the gel for 4 months and take utrogestan 25 days out of 28 as post menopause.  For the last couple of weeks I have a constant feeling that a period is starting but nothing. Don't know whether to be worried about this as haven't had a period for 5 years.

Lesley
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Butterfly22

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #27 on: April 15, 2013, 09:01:02 AM »

I no im confused, i just feellike my body needs one, ive been few years without but did have one when on the sandreana gel, wonder if i should go back to doctors! x
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Cassie

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #28 on: April 15, 2013, 07:11:19 PM »

lila how many days ago did you stop the utrogestan?
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Cassie

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Re: Estradiol gel and progesterone tablet advice please? x
« Reply #29 on: April 15, 2013, 07:14:27 PM »

meno lesley I dont think that you should get a bleed as you are on the utrogestan continuously but it can have those side effects, one gets lots of lower abdominal period type pains with using it, am sure that you will be fine.
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