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[jinkx]

Any help would be much appreciated as I don't know if I'm just worrying to much.  I'm 52 and for three years been on Estradiol gel 2 pumps a day and Progesterone pills 25 days on 3 days off.  My periods stopped in 2020, but last year out of the blue May 2024 I had a very heavy bleed. The doctor sent me for an urgent cancer referal and all  tests came back negative and was told there was nothing to worry about and said bleeding can just happen.  I had no more bleeding until the start of this month August 2025 and have had heavy bleeding for 23 days, to the point I am wearing night time pads changing every few hours with major camps.  I was told by the doctors this can just happen don't worry, but I'm not sure if they are fobbing me off.  I wouldn't be so worried but my mother had uterus cancer at 40 and had a full hysterectomy, then her sister- my aunt died at 56 from uterus cancer.  I don't want to worry but I can't help thinking I might be missing early warning signs.
Has anyone else had this kind of bleed so far apart? Any info, help or advice would be much appreciated.  Thank you in advance.

[Ayesha]

I assume they were aware of your family history. I would say you're not overthinking given your family history and if the bleeding continues then go back to your GP, anything sinister then you are ahead of the game at least.

[bombsh3ll]

I would go back, ask to be investigated again for postmenopausal bleeding and also request to be referred for testing for Lynch syndrome in view of your family history.

Make sure the family history - what relative, what age, cancer type is documented in your medical records.

Personally in your position I would opt for a progestin for endometrial protection rather than micronised progesterone.

This could be a mirena IUS or an oral progestin such as desogestrel 150mcg, drospirenone, norethisterone or provera.