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Estrodiol vaginal creams
Estradiol is often prescribed for vaginal use to treat moderate to severe symptoms of vulvovaginal atrophy, such as dryness, irritation, and painful intercourse (dyspareunia). These symptoms are usually due to a decline in local estrogen levels during menopause. While estradiol is a potent estrogen and can affect the body systemically when taken in larger doses, low-dose estradiol vaginal creams are designed to deliver estrogen directly to the vaginal tissues with minimal absorption into the bloodstream. This localised approach helps to manage symptoms effectively in the vaginal area without significantly raising systemic estrogen levels. Estrodiol used vaginally can provide stronger relief for those with severe symptoms than estriol, especially in cases where estriol hasn’t been effective enough.
Estriol Vaginal Creams
Estriol, being a weaker estrogen, is often used specifically for vaginal symptoms, especially in women who prefer a milder option or are sensitive to higher levels of estrogen. Its low potency makes it ideal for those who need targeted, local treatment with minimal risk of systemic effects. Estriol creams are frequently recommended for women with mild to moderate vaginal symptoms and are seen as a safer option for long-term use in vaginal application. Some women also prefer estriol due to its lower risk of pigmentation issues or other skin-related side effects.