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Author Topic: Taking half a dose of HRT  (Read 149 times)

Helen J Minett

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Taking half a dose of HRT
« on: October 25, 2024, 01:19:44 PM »

It took many years and many attempts to find a HRT method that worked and did not give me severe headaches after a few months. My current prescription which I have been on for a few years is combined Estradoil 1mg/norethistrone acetate 0.5mg. Kliovance. I had been on it for four months and the headaches started again and in desperation to find a solution I started halving the dose. Basically I snap the tablet in half and take half a day. No more symptom and no more headaches. My GP is concerned that I am not getting the protection that a full dose of progestogen would offer. In addition,  I have also been diagnosed with fibromyalgia and I suffer from very bad fatigue and almost constant pain. I have seen it suggested that too little Oestrogen can cause fatigue and wonder if half a dose is contributing to the fatigue. Does anyone have any experience or better still can point me to some scientific date about halving the dose.
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bombsh3ll

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Re: Taking half a dose of HRT
« Reply #1 on: October 25, 2024, 01:45:05 PM »

The only safety concern with halving the tablets is not getting very much estrogen.

If you are ok with with that then it is absolutely fine to either halve your current tablets or ask for a 0.5mg preparation.

I'm not sure if one comes with norethisterone, there might be but certainly femoston do a 0.5 combi tablet with dydrogesterone.

Your GP obviously has a limited understanding around endometrial protection - yes you are getting half the endometrial protection with half a tablet but you are also getting half the stimulation.

This is perfectly ok from an endometrial perspective as the ratio of estrogen to progestin remains the same.
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