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Author Topic: Estrogen levels - max?  (Read 20569 times)

Hollyboll

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Re: Estrogen levels - max?
« Reply #15 on: March 27, 2024, 06:54:11 PM »

Baldrick - that sounds like a very unhelpful GP - if your symptoms return it may well be worth trying a different kind of HRT, not 'just living with it'!!!

I've not used sprays but from my experience with testosterone contaminating and putting everyone into a total panic before they realised it ... if you apply on your inner thigh and wash hands thoroughly afterwards (and for good measure wash your blood arm thoroughly too!) it's not so likely to be contaminating. 

If you are applying at night, I was told by leading meno consultant the best time to do test is next morning - I think  something to do with that being an average of uptake over c24 hours but I'm not sure. 

Also, sometimes there are mistakes.  My own tests were so crazy changing that the first couple of times he dismissed as must be a mistake.

So fwiw and if you can manage it I'd have another test you’re a million percent sure not contaminated (washed hands/ arm etc) and then you have a reference.  If on 2 sprays consistently you still get symptoms and the advice is then not to go up on sprays, might be worth trying another method. 

Just a thought - I've been told I have very unusual absorption issues (on patches) and discussed the different patterns and possibilities a lot while people tried to work out what going on ... but i've not heard of patches 'stopping being absorbed'.  Doesn't mean it's not possible, but ... consultant specifically said he wasn't sure why patches helped me for a while and then didn't - but most likely down to they were good when on sensible doses but caused massive problems when pushed a lot higher.  Anyway, just a long way of saying is there any chance you hadn't in fact stopped absorbing but were for example taking tests on day 3/4 instead of day 1 / not consistent, or needed a higher dose? 

Can you get a referral to a menopause clinic (consultant)?  The waiting lists are long but if your GP will co-operate it's worth getting into the system / on the way ...

HTH x

« Last Edit: March 27, 2024, 07:32:45 PM by Hollyboll »
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Madge79

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Re: Estrogen levels - max?
« Reply #16 on: April 06, 2024, 06:37:03 AM »

Hey
My menopause specialist (and my well informed GP) told me lenzetto is incredibly unreliable when it comes to blood tests. It works in a different way to the gel and patches it creates a kind of reservoir of estrogen under the skin when you spray it on. So blood tests don’t always show as stable. Also if you are spraying on your inner arm and it’s close to the blood draw site it’s very possible the blood test is picking up some of the reservoir in the skin and showing a false high.
My specialist said the only way to really get a realistic idea of levels is to use a patch.
Hope you get it sorted x
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Alex 2024

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Re: Estrogen levels - max?
« Reply #17 on: April 06, 2024, 08:37:18 AM »

Hi All,

I am on Lenzetto as about a year ago I stopped absorbing the patch.

Hi @Baldrick11
Can I ask how you know you stopped absorbing the patch? - I'm wondering if that's what might have happened to me.  3 years ago my oestrogen was tested and it was 866 on Everol patch 100.  So I reduced to 75 and my anxiety decreased with it (thank God!) . I recently upped back to Everol 100 as I had started again with the worst night sweats I've ever had as well as hideous anxiety.  After a month blood test came back as 566 .... I wasn't expecting this. By the way upping Everol didn't help the night sweats or the anxiety..... it's a long story and this is my first post so I wanted to ask here but am also going to start a new post as I feel my medication is complicated at the moment and also don't want to hijack your thread ;) 
TIA x
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Madge79

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Re: Estrogen levels - max?
« Reply #18 on: April 06, 2024, 09:14:42 AM »

Alex this is totally normal, your own body will probably still have been producing more of its own estrogen when your levels were higher. As time goes by this amount drops and then you need to increase your dose to make up for that.

It’s probably not that you stopped absorbing, I don’t absorb well (I never have) and my levels have never been over 300 on 200 patch! If you weren’t absorbing chances are your levels would be much lower.

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Alex 2024

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Re: Estrogen levels - max?
« Reply #19 on: April 06, 2024, 12:48:07 PM »

Thanks Madge, I didn't know that, that's really helpful x
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Madge79

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Re: Estrogen levels - max?
« Reply #20 on: April 06, 2024, 07:19:36 PM »

No worries it’s very common this happens usual a couple of years after starting HRT. Mine has been a nightmare I just can’t get it up any higher 😩. Hope you feel better soon x
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joziel

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Re: Estrogen levels - max?
« Reply #21 on: April 07, 2024, 06:43:25 PM »

Made, it's good to hear from another poor absorber... I'm on 9 pumps of gel now, with advice to go to 10 pumps in a couple weeks if symptoms continue.  ::) ;D  Estrogen is around 430pmol at 9 pumps.

Switching to another product feels like going back to the drawing board in terms of finding the right dosage now I've finally started to see an improvement from 8 pumps upwards(!), but if I need more than 10 pumps I probably will need another product because I'm so fed up of applying gel and waiting for it to dry twice a day....  ::)
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