Hi Everyone. Wondering if anyone can help or give some advice. I had a hysterectomy 20 years ago at the age of 34 due to a large (benign) fibroid. I started hot flushes around 18 months ago and my GP prescribed 40mg Elleste Solo patches to be changed twice a week. The last 6 months, I've been plagued with brain fog, clumsiness and I ache from head to foot. I feel like an 80 years old rather than a 54 year old. My neck cracks and crunches, my knees are sore, if I roll onto my hips during the night the pain wakes me up. My wrists and finger joints hurt. I started to wonder if I had Lupus or Fybromyalgia but following a webinar at work on Menopause last week, I suddenly thought, maybe it's menopause related and the patches just aren't cutting it anymore. I spoke to my GP and she advised she would prescribe me Estradot 75mg patches. These aren't currently available so the suggestion was made to put on 2 x 40mg Elleste Solo patches. I did this for the first time yesterday. Last night I hardly slept and today I have a cracking headache - but this could be just tiredness. Just wondering if anyone else has any experience of having their dose doubled and if they experienced any side effects or if indeed it helped with aches / pains / libido and how long it took before you noticed a difference? Medical history is I am on Sertraline for depression and various other drugs for Coronary Heart Disease. Any help or advice would be gratefully received. Thanks in advance, Lisa. x