Please login or register.

Login with username, password and session length
Advanced search  

News:

Menopause Matters magazine ISSUE 62 out now. (Winter issue, Dec 2020)

twitter facebook instagram blogger

Pages: 1 [2] 3 4 ... 11

Author Topic: Is this the right place to discuss compounded hormones?  (Read 4638 times)

GypsyRoseLee

  • Member
  • *
  • Posts: 2145
Re: Is this the right place to discuss compounded hormones?
« Reply #15 on: March 02, 2020, 08:18:13 PM »

StellaJane, my Mum used Revlon eyeshadow and mascara for 20 years. Then one day, she woke up with two very puffy and sore eyes. By a process of elimination she discovered she had become allergic to her eye make up! Her GP said it often happened especially to ladies of a certain age...interesting my Mum's allergy happened at the same time her periods went erratic in her late 30s.
Logged

Mary G

  • Member
  • *
  • Posts: 1825
Re: Is this the right place to discuss compounded hormones?
« Reply #16 on: March 02, 2020, 08:27:40 PM »

Thanks GRL. I am monitored far more rigorously than I would be with the NHS.  As far as I can make out, the NHS do not monitor women on HRT with uterine scans etc and there is no guarantee women are sticking to the prescription and many probably cheat and take far less progesterone that prescribed - I should know, I have done it myself due to migraines. 

These private clinics have their reputation to protect and if they were putting womens' lives at risk in any way then believe me, a rag like the Daily Mail would be all over it.

BeaR, that sounds very interesting, I look forward to reading your material.
Logged

Perinowpost

  • Member
  • *
  • Posts: 540
Re: Is this the right place to discuss compounded hormones?
« Reply #17 on: March 02, 2020, 08:30:17 PM »

Very interesting post MaryG you tackle perhaps the most frequently asked question on this forum, that of progesterone intolerance.

Like you I know that bespoke options are not 'signed off? so to speak by the powers that be, but that is because it is so hard to regulate and not because the particular regime that you have discovered does not work. And of course as you so rightly point out you are being closely monitored.

I myself am currently investigating a bespoke regime regarding progesterone, after trying and failing with everything currently available on the nhs.

Surely the bigger question - and I've said it on here many times before - is when are we going to have more viable prog options for this very real problem. Then and only then we won't have to go outside the box/pay to feel well x
Logged

KBallinger

  • Member
  • *
  • Posts: 39
Re: Is this the right place to discuss compounded hormones?
« Reply #18 on: March 02, 2020, 09:24:24 PM »

Thank you stellaJane and Wrensong for your kind words.

Thank you Hurdity I will post more about myself in the private Lives section as I'm not sure there are too many kballinger's in the world and would hate some of the details to be seen by work colleagues and friends family I have not shared such info with.

X
Logged

KBallinger

  • Member
  • *
  • Posts: 39
Re: Is this the right place to discuss compounded hormones?
« Reply #19 on: March 02, 2020, 09:28:25 PM »

GypsyRoseLee I can totally relate to how much you have suffered due to progesterone. I would not wish it on my worst enemy. Sorry you had to go through that. X
Logged

Wrensong

  • Member
  • *
  • Posts: 1023
Re: Is this the right place to discuss compounded hormones?
« Reply #20 on: March 02, 2020, 09:31:39 PM »

Glad Hurdity's been along to meet you, KBallinger.  Do post again.
Wx
Logged

dangermouse

  • Member
  • *
  • Posts: 1060
Re: Is this the right place to discuss compounded hormones?
« Reply #21 on: March 02, 2020, 09:32:31 PM »

It is a shame that the British Menopause Society have taken such an extreme stance against compounded products, they also mention saliva testing which is nothing to do with UK BHRT clinics so I'm not sure where theyre getting their info from? Maybe the US.

NICE do not hold such strong views against BHRT, they just say that practitioners should make it clear to patients that BHRT is not regulated, they do not state that it should not be prescribed.

The BMS is not a government organisation, simply a society that menopause practitioners (not just docs) can choose to pay to join for advertising their services, industry updates and access to seminars etc. They are supported by the practitioner fees and seminars but they also receive occasional funding from the regulated HRT manufacturers (like Besins) so there could be financial conflict of interests at play.

Im sure that Prof Studd would like to be able to offer the 50mg progesterone but then he couldn't be promoted by the BMS as, although you can be a member for the other benefits, you can't be on the practitioners list if you prescribe BHRT.

Im not saying that the BMS should promote online products (although they do promote Sylk and YES) but they could be open to products made in specialist compounded pharmacies via GMC registered UK doctors, for example.

Fortunately, on an open forum we can learn from each other and not be restricted by corporate vested interests.
Logged
50, perimenobloodypausal.

CLKD

  • Member
  • *
  • Posts: 61711
Re: Is this the right place to discuss compounded hormones?
« Reply #22 on: March 02, 2020, 09:36:46 PM »

 :thankyou:  dangermouse - that's the best bit of info I've read today  :foryou:
Logged
Changes can be scarey, even when we want them!

Perinowpost

  • Member
  • *
  • Posts: 540
Re: Is this the right place to discuss compounded hormones?
« Reply #23 on: March 02, 2020, 10:06:13 PM »

Yes, puts it all into perspective Dangermouse x
Logged

Ladybt28

  • Member
  • *
  • Posts: 1496
Re: Is this the right place to discuss compounded hormones?
« Reply #24 on: March 02, 2020, 11:18:02 PM »

I heard from elsewhere the other day that Professor Studd has retired. Anyway I digress.  I find it a bit weird that utrogestan is "micronized" progesterone and supposed to be as close to the type the body can produce.  Surely the issue (regulation aside) is the doses that it is manufactured in.  A 25mg utrogestan pill or a 50mg Utro pill would likely beneficial to some women.

MaryG or someone (one of you clever pharma ladies  :)) can you tell me what these bio identical lozenges contain?  Is it something different from "micronized progesterone" which I understand to be very different from synthetic progesterone which is different again?
Logged

GypsyRoseLee

  • Member
  • *
  • Posts: 2145
Re: Is this the right place to discuss compounded hormones?
« Reply #25 on: March 03, 2020, 10:35:26 AM »

Fabulous post dangermouse. I think it behoves us all to remember that enormous sectors of the NHS are very much money orientated, and we are all subject to the post code lottery when it comes to the availability of treatment and medications, sadly.
Logged

Tc

  • Member
  • *
  • Posts: 2368
Re: Is this the right place to discuss compounded hormones?
« Reply #26 on: March 03, 2020, 11:16:34 AM »

Great thread. I'm wondering where the E implant I'm now on comes into this picture.

I had thought  in regards to estradiol only that  all the patches and gels available on NHS were BHRT. And that it was only tablets like premarin that wasnt. 

Very interesting posts ladies. X
 




Logged

Mary G

  • Member
  • *
  • Posts: 1825
Re: Is this the right place to discuss compounded hormones?
« Reply #27 on: March 03, 2020, 12:22:41 PM »

Excellent post dangermouse but the cynical side of me is not surprised.  It explains an awful lot doesn't it.

Ladybt28, it is body identical progesterone but my experience with this product does not resemble my experience with vaginal Utrogestan in any way, shape or form.  This is partly due to the dose (50mg) and the buccal (between top lip and gum) delivery system.  Some women who need a higher dose of progesterone take 50mg  every 12 hours.

After day 3 of Utrogestan, I used to feel myself gradually slipping away and it was seriously scary stuff.  I used 100mg vaginally but it hardly made any difference to the side effects, the worse of which were silent migraines.

I wonder why so many women react so badly to Utrogestan?  Is it because the dose is way too high?  Obviously not everyone has a problem with it but it's the most frequent problem on MM. 
Logged

dangermouse

  • Member
  • *
  • Posts: 1060
Re: Is this the right place to discuss compounded hormones?
« Reply #28 on: March 03, 2020, 12:45:41 PM »

The progesterone lozenges that I have seen are micronized progesterone in a wax-like substance but I think there are other presentations. The main thing is that progesterone needs to be suspended in something like Vitamin E for sublingual absorption and then that needs to be coated for however it is being absorbed. The Ultrogestan is in a dissolving capsule for the stomach and I guess the acid in the vagina is enough to melt it too.

Transdermal creams can also be sufficient for womb protection if they use decent carriers and if the individual patient absorbs it well. I had read that transdermal did not suit progesterone but then tried a compounded one and my levels went very high.

At London Hormone Clinic I was offered 25mg progesterone lozenge (once it had built up in system) versus a 25mg oestrogen patch, if I had wanted to take HRT. Then if any womb build up they would obviously go higher with the prog.

I think the main difference with private BHRT clinics, as many have said here, is that they give you a lot of time and see you frequently at the beginning which is all embedded in the cost. This means they can give you the smallest dose of HRT to control your symptoms, rather than how the NHS have to use higher doses of progesterone to over-protect the womb because there are not enough resources to keep an eye on any womb build up, so it may be more for keeping testing costs down than them not bothering to try to source a lower dose.

Its a bit like how cheaper clothes are made in one size only, for some it can work but for others they need to have the specific size to look ok and so choose to pay more.
Logged
50, perimenobloodypausal.

Mary G

  • Member
  • *
  • Posts: 1825
Re: Is this the right place to discuss compounded hormones?
« Reply #29 on: March 03, 2020, 12:55:49 PM »

KBallinger, I'm sorry, I forgot to say that it sounds like you are in the last chance saloon progesterone wise so bespoke progesterone might be worth considering before opting for surgery.   

It's interesting that like me, you could tolerate the Mirena coil pre menopause.  It could be that we have a similar problem.
Logged
Pages: 1 [2] 3 4 ... 11