Hello DBean
I'm a relatively new patient of Professor Studd's (since last October), and am on the exact same combination/dose as you.
My hot flushes, night sweats, terrible sleep, anxiety, fogginess, lack of energy, aches, feeling down all disappeared pretty much completely within about three weeks, although within a few days I felt significantly better. In fact, I felt really amazing for about two months, but then ran into some problems (upset stomach, sleep disturbances) and I'm trying to work out what's going on.
I apply the gels at night, but don't have any transfer risks as sleep alone.
Hope that helps,
luna x