Hi
I'm not very knowledgeable on hrt but I am suffering the same as you. I'm also 48, peri and off work. I do know the femseven sequi does not come in a higher dose and the evorel sequi has a harsher progesterone. I am currently on oestrogel and utrogestan ( progesterone) but due to being given a different make of oestrogel I'm suffering this week.
If you want transdermal you could ask for a separate estrogen patch or gel with either utrogestan or provera as the progesterone
Good luck x