Hi everyone,
I'm 53 and have been using oral combi conti HRT for one year with excellent results until about 3-4 months ago.
Within a week of starting in April 2016 many of my symptoms (hot flushes, night sweats, mood changes, joint pains, energy levels etc) had all resolved. Very satisfied customer! And happy family/co-workers too!
However about 3 or 4 months ago I felt as if the effect was wearing off. Thats the only way I can describe it. Night sweats started up again and disturbed sleep and low mood/irritability/anxiety. I discussed this with the practice nurse who seemed rather puzzled by my description, as if she hadn't heard of this sort of thing. I asked for a higher oral dose but as I was on top whack that wasn't an option. To be fair, she did say she would seek expert advice and get back to me. As promised she did and the GP phoned me and suggested changing to transdermal patches. I'm now on two patches Evorel Conti and Evorel 50 at the same time.
Has anyone else experience of their HRT "wearing off" or am I imagining this?
I read this may happen with HRT implants (tachyphylaxis) but the scientific evidence is weak. If it does happen, and is not my imagination, will it happen with the patches? Or is it just my oestrogen levels have fallen off a cliff again and I need more to "top up" to my functioning level? If I need more in the future how many patches can a girl use at one time?!?
Thanks for any advice you may have xx