I think I have given you advice before but here goes:
It's probably the fillers in the oestrogen creams that irritate.
I would try Vagifem local oestrogen pessaries as these irritate less - pop back to the nurse and get this.
Keeping the flora balance in the vagina can be difficult when the oestrogen levels drop in peri meno and adding in some systemic oestrogen might be a good idea. However, using vaginal moisturiser daily alongside the local oestrogen is vital to help maintain the flora balance and prevent BV and thrush taking hold. Some like the YES products, I personally love SYLK - I apply SYLK at least 2 times a day. Multi Gyn Actigel is great for preventing and treating BV and thrush but only use this a couple of times a week or daily if infections take hold. Thrush treatments and pills are harsh and will irritate. Don't use Multi Gyn or any moisturisers at the same time as the local oestrogen.
Take showers not baths. Wash with gentle, unscented, products specifically for the ‘lady bits' area.
Never wash you hair in the shower - shampoo will really irritate the ‘lady bits'.
Drink some water with bicarb morning and evening if you are burning. Avoid caffein, alcohol and any fruit juices (too acidic) but drink enough water to help stop any infection taking hold.
After bowel movements, really clean well - most vaginal infections come from the bowel - we women are poorly designed. Eat plenty of yogurt to maintain a positive flora in the gut.
Vaginal moisturisers are often the best way to sooth irritation in the short term - get some YES and some SYLK and see which one suits best. Lots of local, and possibly systemic, oestrogen will help in the long term and should be used regularly. DG x