Just a quick update, I had been using estrogel for 2 years but had lowlevels about 107 and recently started feeling awful, hot and very emotional, anyway received great advice here and have been applying the gel on my inner thigh for last 2 weeks instead of shoulder/arm, 1 pump am and 1 pump pm, after 6 days approx I gradually started feeling much better and now have no hot flushes, awful emotional ups and downs have gone so I am so pleased, I guess I can ask my Dr for another blood test in 3 months to see if my oestrogen level has increased (would be interesting) but certainly looks like it's working on my inner thigh absorbing, I just cannot understand how for 2 years of using the gel hardly anything was absorbed by rubbing on my arm! Just one more thing is that vaginal dryness has come back and it is so sore, I do have an active sex life but it was agony last time, I have read about vagifem, can I use this whilst on my hrt? Many thanks once again for the advice with the gel, 😀