This thread was very helpful when I was deciding whether to HRT or not, so I thought I would add my two-penneth to the debate. I am now on week 6 of Elleste Duet 1mg
Background - 43, hot flushes since I was 38, gave up smoking at 41 and suddenly meno symptoms increased. Depression, anxiety, loss of libido, dryness, inability to think straight...however my periods were every 28 days as they have been since I was 11. I had gained 2 stone as I had give up smoking 16 months previously, however I am a fitness freak and was / am very fit.
Day 2 - I thought I had made the biggest mistake, I seemed to be 'off on one' with major PMT which was very out of character (I still think this was the HRT, but others may say it was too soon to have any effect).
Day 4 - I really started to feel better, I honestly can not explain why and how I felt better I just did. This could be a placebo effect...but who cares.
Week 14 - Huge improvement in my mental health, my well being in general and frankly I found my sense of humour in my sock draw!
The downside though was: a dull headache for the first few weeks but this was not unbearable, very sore heavy breasts, huge water retention making me feel fat and even though I had joined a fat club I was not losing weight, even though I swim a mile every morning and gym / class / spin / run most evenings.
Day 20 - Had bad period pain without the period which was very worrying this continued for another 7 days.
Day 28 - Started period right on schedule, so being on HRT never interfered with my normal cycle. However I had bad period pain for the first 2 days.
Six weeks - Headache gone, no more lower pain, no more sore breasts, no more water retention and I have dropped half a stone in two weeks (with fat club and exercise). Slight improvement in libido but nothing to write home about, however I do live in hope.
HRT is a very personal thing, however at 43 with a career, a social life and a great marriage I was not prepared to live my life with depression, anxiety, mood swings AND become just another grumpy middle aged woman. Each to their own, however I have no problem with the heath scares as I have smoked, I have had too much sun, I have drank and eaten the wrong things and I could get hit by a bus tomorrow.
I will update in a month xx