It has been very good for me. Was peri-menopausal at 47 in 2013 and prescribed Prempack C - I was so lucky, I had no problems at all. Disaster has struck this week however - I went to collect my HRT from chemists - and opened at home to find Indivina 1mg/2.5mg. Never heard of it. A call to the GP today has informed me that Prempack C is no longer available. This I understand, but that no one contacted me to discuss making changes has infuriated me! I have been given an 'emergency' appointment this afternoon to discuss. I will make a complaint - the prescription was written by a GP I have never met, no questions asked about my current state - how dare a GP minimise and make such assumptions about MY menopause! He's on holiday - or so I have been told. I am angry about this, and also so concerned that if I were less assertive, I would probably just go along with it, which leaves other women vulnerable to the whims of poor GP practice. I don't know if Indivina is appropriate, any idea? I also have MS so I really don't need my hormones messing with!