Oestrogel and Oestrodose have different forms of oestradiol:hemihydrate and anhydrous respectively. I have no idea whether that has any relevance in practice and initially when I first tried Oestrodose, I didn't notice any difference. After about a month, I noticed that I was getting more brain fog. This eased when I went back onto Oestrogel but the same thing happened the next time I used Oestrodose. I don't absorb very well, so that may be a factor. I certainly groan when I see I've been given Oestrodose instead, but like you, I've got enough Oestrogel to not have to use it at the moment. If you say anything to the pharmacist, they just insist it is the same.