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[common-lime]

Asking you lovely lot because this is a more UK heavy forum than some

I've been on 2 pumps oestrogel and 100mg progesterone (generic, but looks identical to Utrogestan) for a few months. I'm only in peri but taking the progesterone continuously because of heinous mood swings on cyclical, plus continuous makes my endometriosis behave so much better. I have no complaints around mood/anxiety on this regime, it's been brilliant. Physically though, I had much worse muscular and joint pain in the progesterone phase of the cyclical regime, and that hasn't got better on continuous.

Is this a thing that taking progesterone vaginally can help with? Are the 100mg soft caps safe to take vaginally, or does it really need to be branded Utrogestan? The endometriosis makes me especially wary of messing with something which is at least a 75% improvement over my starting point! The pain is getting to me a bit though.

[CLKD]

Usually it's a loss of oestrogen that causes joint pain as muscles may become lax.

R any particular joints/areas affected?

[common-lime]

That's the weird bit, I do think it's more muscular than joint pain. Everything hurts! I would worry about chronic illnesses if it wasn't for the fact that it disappeared during the oestrogen-only parts of my couple of months on sequential HRT. I did have some more focused joint pains (feet, hips, neck), before HRT and those aren't bothering me as much, but instead I constantly feel like I've been lifting weights in my sleep lol.

[CLKD]

OK Granny here suggests: checking that your footwear is appropriate: that your seating and sleeping positions are correct.

Years ago I woke with such deep pain in the thigh that I was unable even to yell, fortunate as we were in B&B at the time  eventually I realised that it was being caused because I leaned over too often, particularly when looking in cabinets at antique fairs.

It would seem that your problems are hormonal ........... have U tried over the counter pain relief prior to exercise, mowing the lawn etc.?

[common-lime]

I forgot to thank you for your suggestions! All very sensible 

I wanted to try the progesterone vaginally as well as trying to keep tabs on my posture etc (shoes really do make a difference - not that I was ever into heels or anything like that, but insoles are great things!). My joint pain has disappeared  I am a bit hypermobile and I wonder if the oral metabolites of the progesterone were interacting with that somehow. So that's great - but my period has also disappeared, which was unexpected. Sitting here on day 42 (I'm usually 25ish days) with nowt but a migraine to show for the usual build up to hormomal chaos. Weird.

[bombsh3ll]

Progesterone is well known for exacerbating joint and ligament laxity.

This is physiological, as the pregnancy hormone it helps our pelvis accommodate and expel a baby.

If you have any degree of joint laxity, progesterone is not your friend. It is also the least effective progestogen for controlling endometriosis.

I would consider switching to an androgenic progestin, which would ideally provide menstrual suppression as well, and also consider adding in testosterone which can be really helpful with joint laxity and pain.