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Author Topic: Endometrium too thick and stopping hrt advice please 🙏  (Read 2575 times)

Mary G

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Re: Endometrium too thick and stopping hrt advice please 🙏
« Reply #15 on: July 13, 2025, 07:09:09 PM »

Cassie, I take it you are asking about bespoke, compounded progesterone?  This might interest GalwayGirl too.

I will bump up my thread on this subject in the Alternative Therapies section but I successfully used buccal progesterone lozenges @ 50mg every day until I was no longer able to obtain them due to Brexit.  I found that dose adequate for womb protection and free of side effects when used with two pumps of Oestrogel and my uterine scans invariably came out at 3mm (ish).  The clinic I used have now successfully developed a progesterone cream and sublingual drops.

The Darstin progesterone gel (not available in the UK) is not as strong but I was doing fine on four measures every day and occasionally interspersing with 50mg Cyclogest.  However, two things happened (a) I had to increase to two pumps of Oestrogel because one pump was not enough to prevent my brain stem auras and (b) bomb helpfully mentioned Cerazette and its lack of side effects.  So now I use two pumps of Oestrogel, one 75mcg Cerazette every day, testosterone and two measures of progesterone gel and it's working well.  I am on a continuous combined regime.

Assuming you are still using one pump of gel every day and wanting to substitute Utrogestan (I hope my memory serves me correctly) 50mg on a cycle (probably for 12 days) would work and equally you could use it continuously which should be free of side effects - I found it was nothing like Utrogestan.  Obviously regular TVS scans are recommended. 

I would definitely recommend the lozenges.

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