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Menopause Matters magazine ISSUE 81 out now. (Autumn issue, September 2025)

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Author Topic: Vagifem stopped working?  (Read 3643 times)

Anabelle31

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Vagifem stopped working?
« on: January 12, 2025, 09:06:45 PM »

I posted a while ago about feeling like I had a uti all the time but never actually having one. Docs kept finding microscopic blood in urine but all tests came back clear. Currently gynaecologist says I’m in perimenopause and started me on vagifem 2 months ago. It’s worked brilliantly for burning and frequency but the past few days it’s come back and I feel really disheartened. Has this happened to anyone else? I run a lot and it seems like maybe running several days in a row kicked it back off. Thanks for any help.
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VioletAquarius

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Re: Vagifem stopped working?
« Reply #1 on: January 12, 2025, 10:12:29 PM »

How many times per week do you use it?  You may have to increase the amount of times you use it.
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Ayesha

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Re: Vagifem stopped working?
« Reply #2 on: January 12, 2025, 11:06:06 PM »

Exercising or any other hard physical activity can easily start it off. You probably need to increase your dose of Vagifem, if you are using two pessaries a week its usually not enough.
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Anabelle31

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Re: Vagifem stopped working?
« Reply #3 on: January 13, 2025, 10:31:23 AM »

Violet - 3 times a week which doc was unhappy about. Insisted it should be 2.

Ayesha - exercise is my suspicion but can’t find any evidence online for this. Not much talk of blood in urine for that matter.
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Ayesha

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Re: Vagifem stopped working?
« Reply #4 on: January 13, 2025, 10:54:43 AM »

There is not much online about the symptoms apart from the obvious but I do remember the terrible pain I ended up in after a hard days gardening, the constant bending down caused a lot of discomfort to the point I couldn't sit down by the evening and I also had the blood in urine too, so don't worry about that as its normal with GSM.

I think a lot of GP's connect topical oestrogen to systemic, both are totally different in use, its the word hormone that connects them. Topical is safe to use, if it wasn't you would not be able to buy it over the counter. If you can afford the freedom to buy it then do so, GP's are hopeless but Nurse practitioners can be amazing, speak to them if you can.

I know I am like a broken record but here is the link to the guidelines I follow in my treatment approved by my surgery and my wonderful NHS Nurse Practitioner.

https://bssm.org.uk/wp-content/uploads/2023/02/GSM-BSSM.pdf

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SundayGirl

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Re: Vagifem stopped working?
« Reply #5 on: January 13, 2025, 02:33:57 PM »

You're definitely not a broken record Ayesha.

A lot of ladies are left in discomfort due to GPs not prescribing enough local oestrogen to control symptoms while dishing out other drugs like they're sweets.

Annabelle31 - can you speak to a different GP at your practice? Very often they differ in their views and prescribing practices.
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CLKD

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Re: Vagifem stopped working?
« Reply #6 on: January 13, 2025, 02:49:05 PM »

Annabelle - change your GP!  Pronto!  Then stick his/her head down the loo and flush.  Several times  >:(

One can use VA treatment every night if necessary.  When I get symptoms I pop a dose up mid afternoon and again every night for at least 5.  Not something that I discuss with my GP.  Repeat is issued without question.
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Anabelle31

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Re: Vagifem stopped working?
« Reply #7 on: January 13, 2025, 06:27:36 PM »

Thanks both - it’s just so frustrating. Doc says I’m too young and it only happens post menopause (I’m 41). Mother went through menopause early though. Keep insisting microscopic blood can’t be related, though they can’t find another cause. Fed up of it!
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SundayGirl

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Re: Vagifem stopped working?
« Reply #8 on: January 13, 2025, 06:34:52 PM »

Your doctor is talking absolute rot when saying it's only happens post-meno.

Speak to a different GP at the practice. You shouldn't have to suffer when there's a solution available.
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joziel

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Re: Vagifem stopped working?
« Reply #9 on: January 13, 2025, 10:36:08 PM »

Anabelle, this is total crap from your GP. Don't accept it. You should be on daily local estrogen if you need it. It's incredibly safe. I needed it from 42. (Well, now I don't need it at all because I"m on systemic HRT and have plenty from that - but when I was on a tiny starvation dose of HRT I did need the local E as well.)

It's worth listening to the podcasts and YouTube vids made by Dr Felice Gersh by the way. She says that if you need local E, your systemic E is not high enough. If you have enough systemic E to get everywhere it needs, it should treat the vag as well. And the problem is the tiny systemic doses in modern HRT because most doctors are terrified of estrogen.

But that's a slightly different subject for you right now.

I highly recommend going private to the Newson Clinic and getting them to write a letter back to your GP, telling your GP to prescribe local E daily. Your GP doesn't have to take that advice but mine has with my HRT protocol, which is very high dosage. Try to find a better GP who will work with you, though. Because even if you go private it helps to have an NHS GP who will continue that private prescription on the NHS. If you have a GP as you describe, you will come up against obstacles over and over again.
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Anabelle31

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Re: Vagifem stopped working?
« Reply #10 on: January 13, 2025, 10:47:28 PM »

Anabelle, this is total crap from your GP. Don't accept it. You should be on daily local estrogen if you need it. It's incredibly safe. I needed it from 42. (Well, now I don't need it at all because I"m on systemic HRT and have plenty from that - but when I was on a tiny starvation dose of HRT I did need the local E as well.)

It's worth listening to the podcasts and YouTube vids made by Dr Felice Gersh by the way. She says that if you need local E, your systemic E is not high enough. If you have enough systemic E to get everywhere it needs, it should treat the vag as well. And the problem is the tiny systemic doses in modern HRT because most doctors are terrified of estrogen.

But that's a slightly different subject for you right now.

I highly recommend going private to the Newson Clinic and getting them to write a letter back to your GP, telling your GP to prescribe local E daily. Your GP doesn't have to take that advice but mine has with my HRT protocol, which is very high dosage. Try to find a better GP who will work with you, though. Because even if you go private it helps to have an NHS GP who will continue that private prescription on the NHS. If you have a GP as you describe, you will come up against obstacles over and over again.

Thank you this is really helpful. I think because of the blood in urine, my GP didn’t think menopause at all and just sent me for battery of tests re bladder etc. I did eventually see a private gynaecologist who said my estrogen was low and prescribed HRT - 2 pumps gel daily, 2 weeks of  progesterone a month. I’ve been on that a month now. Been using vagifem for 3 months and it’s been great until this week. Disheartened to think maybe I have to give up running. Will make an appointment with Newsom and see what they say. Thanks again!
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joziel

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Re: Vagifem stopped working?
« Reply #11 on: January 14, 2025, 08:40:59 PM »

Recurrent UTIs are a major symptom of low estrogen. Check out Dr Kelly Casperson on Instagram. She's a US based urologist who has a lot to say about vaginal E and HRT. She's there as kellycaspersonmd
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Anabelle31

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Re: Vagifem stopped working?
« Reply #12 on: January 15, 2025, 12:05:48 AM »

Recurrent UTIs are a major symptom of low estrogen. Check out Dr Kelly Casperson on Instagram. She's a US based urologist who has a lot to say about vaginal E and HRT. She's there as kellycaspersonmd

Thanks. I don’t actually ever have a uti. Just the microscopic blood.
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joziel

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Re: Vagifem stopped working?
« Reply #13 on: January 15, 2025, 11:30:33 AM »

That could be due to vaginal atrophy. When the skin gets really thin in the vagina, it can bleed like that. Think of cracked sore hands......
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Anabelle31

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Re: Vagifem stopped working?
« Reply #14 on: January 15, 2025, 11:50:57 AM »

That could be due to vaginal atrophy. When the skin gets really thin in the vagina, it can bleed like that. Think of cracked sore hands......

That’s what I think. But that’s why it’s so frustrating that after 3 months on vaginal estrgoen working so well, the feeling is back. Grrr!
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