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[Tribbins]

Hi Twinkle82, I'm not really sure how long it's taken - as I started reducing oestrogen after about 10 days (I just don't want a mirena, so stopping the lot) - So probably a couple of weeks to completely get out of the progesterone hangover, and stop having low thoughts and the intrusive type thoughts. I was also waking at 4am for a while, which seems to have stopped in the past couple of days. I hope it improves for you soon - remember, this too shall pass!

[Twinkle82]

Thank you! Definitely need to hear that! I had a mirena about 6 years ago and was fine on it. Second time around after second baby and turning 40, absolutely terrible. Because the prometrium is meant to be body identical I thought I might be ok on it but no! Glad to hear you’ve stopped waking at 4am! That’s a win!

[AnonoMiss]

Hi Twinkle82, I'm not really sure how long it's taken - as I started reducing oestrogen after about 10 days (I just don't want a mirena, so stopping the lot) - So probably a couple of weeks to completely get out of the progesterone hangover, and stop having low thoughts and the intrusive type thoughts. I was also waking at 4am for a while, which seems to have stopped in the past couple of days. I hope it improves for you soon - remember, this too shall pass!

I've had a similar horrendous experience with Progesterone it seems for some due to progesterone acting on GABA /Glutamate it can create a type of tolerance so when stopped there is a withdrawal

How did you get on and how are you now?

The FB group Progesterone Withdrawal might be of interest!

[AnonoMiss]

Have noticed this month that 5 days after stopping Utro I suddenly went very downhill moodwise and felt anxious and jittery again ( having felt great for the last 4 weeks). It only lasted 24 hours but was pretty unpleasant.

Just wondered if it was progesterone withdrawal? It would also have been day 4 of my bleed and I'm sure I've read that your oestrogen is at its lowest in about day 3/4 of your period?

Could there be a connection there? And anyone else get that nasty slump in mood and anxiety during their bleed?

I've had a similar horrendous experience with Progesterone it seems for some due to progesterone acting on GABA /Glutamate it can create a type of tolerance so when stopped there is a withdrawal

How did you get on and how are you now?

The FB group Progesterone Withdrawal might be of interest!

[AnonoMiss]

After a few months of HRT I definitely developed progesterone withdrawal - bit ironic given that I thought I'd react to actually taking it, not stopping taking it. I think it was worse cos my own hormones were still there mucking around in the background. Qlaira has helped as there are more days with the combined drugs, but ideally, I'd like to take both every day. Do you notice the withdrawal affects your hair and nails too?

I've had a similar horrendous experience with Progesterone it seems for some due to progesterone acting on GABA /Glutamate it can create a type of tolerance so when stopped there is a withdrawal

How did you get on and how are you now?

The FB group Progesterone Withdrawal might be of interest!