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Author Topic: Options for progesterone intolerance?  (Read 1154 times)

kittydaydream

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Options for progesterone intolerance?
« on: August 15, 2024, 09:08:22 AM »

Hi all, some advise please, I’m peri and on 100 estraderm patch and continuous Utrogestan- I have awful symptoms from it and have tried Provera and that was worse, I’m waiting for appointment for mirena but it may be a month or two! Has anyone found anything they tolerated better?
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CLKD

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Re: Options for progesterone intolerance?
« Reply #1 on: August 15, 2024, 11:25:58 AM »

Now I am confused, have U not put a similar query on here already  :-\
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kittydaydream

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Re: Options for progesterone intolerance?
« Reply #2 on: August 15, 2024, 11:31:58 AM »

I have! This is the level of my desperation!
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kittydaydream

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Re: Options for progesterone intolerance?
« Reply #3 on: August 15, 2024, 11:34:45 AM »

Desperate for a Utrogestan alternative while I wait for mirena, I think my posts have been consistent, I’m just really struggling
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kittydaydream

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Re: Options for progesterone intolerance?
« Reply #4 on: August 15, 2024, 11:40:49 AM »

Menopause clinic is over a years wait and I can’t afford to go private right now, thus I’m trying to get more immediate help from this resource
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joziel

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Re: Options for progesterone intolerance?
« Reply #5 on: August 15, 2024, 11:45:22 AM »

All the licensed options are listed here: https://thebms.org.uk/wp-content/uploads/2021/10/14-BMS-TfC-Progestogens-and-endometrial-protection-01H.pdf

See what you want and ask your GP for it.
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kittydaydream

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Re: Options for progesterone intolerance?
« Reply #6 on: August 15, 2024, 11:52:49 AM »

Thanks for that
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bombsh3ll

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Re: Options for progesterone intolerance?
« Reply #7 on: August 15, 2024, 12:09:50 PM »

Don't forget about tibolone, that is loved by many women who can't tolerate progesterone or synthetic progestins.

It is oral but studies showed no increase clot risk.

It has estrogen, androgen and uterine protection all in one pill and I am really interested in it for myself when the time comes to graduate from my OCP.

Nothing to lose by trying it whilst waiting for the mirena.
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kittydaydream

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Re: Options for progesterone intolerance?
« Reply #8 on: August 15, 2024, 12:15:04 PM »

This is true bombshell I’ll ask about it
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Mary G

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Re: Options for progesterone intolerance?
« Reply #9 on: August 15, 2024, 12:16:47 PM »

If you are having a Mirena coil fitted very soon, can't you just skip the progesterone? 

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StrideOrDie

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Re: Options for progesterone intolerance?
« Reply #10 on: August 15, 2024, 03:30:56 PM »

If you're getting the Mirena shortly, just stop taking the utrogestan. You aren't going to get hyperplasia and/or cancer from not taking a progestogen for a couple of months. Confirmed this with my doctor, whom I talked with this AM. No need to torture yourself unnecessarily.

Despite what Big Med has told us, cancer takes years to develop and that's after hyperplasia has already set in and has gone untreated (i.e., women ignoring post-menopausal bleeding until it's too late). Even if you did have hyperplasia when the Mirena goes in, that Mirena is exactly what your doctor would prescribe (or another progestogen) to treat it. This is literally coming from the mouth of a doctor who has me on a 12-days-every-two-months vaginal progesterone routine.
« Last Edit: August 15, 2024, 03:34:02 PM by StrideOrDie »
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Furyan

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Re: Options for progesterone intolerance?
« Reply #11 on: August 15, 2024, 03:32:12 PM »

Don't forget about tibolone, that is loved by many women who can't tolerate progesterone or synthetic progestins.

It is oral but studies showed no increase clot risk.

It has estrogen, androgen and uterine protection all in one pill and I am really interested in it for myself when the time comes to graduate from my OCP.

Nothing to lose by trying it whilst waiting for the mirena.

I recently tried tibolone and it was fantastic in every way other than its estrogenic effects being too weak for me. Apparently my oestrogen needs have gone up over the past year and I got a return of horrendous hot flashes and night sweats on it. When my needs go down again, I’d definitely consider it again.

Coming from 100 patch, I’m not sure tibolone would be enough.
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Hurdity

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Re: Options for progesterone intolerance?
« Reply #12 on: August 15, 2024, 08:08:33 PM »

Yes I agree. Tibolone is pretty low dose for standard post-menopause.

I also have read that there is in fact an increased stroke risk in taking tibolone though I haven't seen the original study - but I understand that for women over 60 the risks begin to outweigh the benefits. There is also increased risk of breakthrough bleeding and in longer term use, over 3 years, increased risk of endometrial hyperplasia cancer - though I'm not sure how this compares with cyclical HRT, nor how this might vary with age.

I agree that if you don't have to wait long for your Mirena, say a couple of months - you won't do any long term harm - your endometrium will just grow and then once you have the Mirena you should get some bleeding as it sheds and thins down, and stabilises ( hopefully!).

Hurdity x
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kittydaydream

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Re: Options for progesterone intolerance?
« Reply #13 on: August 15, 2024, 08:24:59 PM »

Cheers Hurdity gut says hang on xx
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