I have no personal experience with androfeme but I do take dhea for androgen replacement and I also went from very low testosterone levels similar to yours, to now being near the top of the female range.
Whilst I had no mood symptoms, it made a noticeable difference to both my physical and cognitive health over a period of a few months in multiple ways.
I even got my libido back which isn't why I was taking it but it's nice to have!
I would give it at least 6 months before writing it off, but would recommend taking a repeat blood test if you haven't already, to check that you are absorbing it and whether your dose needs increasing if you are still below the therapeutic range.