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Author Topic: Increase? Or just anxiety? Please help me!  (Read 1501 times)

mandamoo85

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Increase? Or just anxiety? Please help me!
« on: April 15, 2024, 07:33:12 PM »

Hey!  :)

So, I struggle with anxiety anyway - I’m on an abundance of drugs. I was having night sweats etc so we tried HRT. It was amazing to start with (50 Evorel). I wasn’t anxious - getting things done.

Sweats came back, increased to 75 Evorel - awful foggy head (that didn’t shift).
So, went to 50 patch and 1x gel but for the past month I’ve been having pangs of anxiety, little wave like panics. It’s exhausting and I don’t know what to do.

Too much? Not enough? I’m 39 - do I need it? I’m so confused.
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CLKD

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Re: Increase? Or just anxiety? Please help me!
« Reply #1 on: April 15, 2024, 07:59:47 PM »

hi!. some cut patches and add a small piece to the 50.  Or apply 50 regularly and 75 occasionally to allow the body to uptake the extra hormone.

Anxiety is exhausting.  'savage' some1 suggested.

Which drugs R U already taking, R they related to HRT?
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mandamoo85

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Re: Increase? Or just anxiety? Please help me!
« Reply #2 on: April 15, 2024, 08:31:57 PM »

Hey, thanks for the reply.
I have a huge list of mental health drugs - sertraline, Quetiapine, Lamotrigine, Pregablin, propanolol.
I’m on 75 (as have the pump too) just wondering if it’s enough. X
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joziel

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Re: Increase? Or just anxiety? Please help me!
« Reply #3 on: April 16, 2024, 10:08:15 AM »

I suspect you might be one of these people Dr Louise Newson talks about, who end up on a variety of drugs when all they really needed was the *right dose* of HRT.

If you're getting night sweats then you most definitely need HRT, that's a classic low E symptom. And it's extremely promising that your anxiety got better when you first started. But like many you probably need an increase and 75 might not be enough.

Have you had bloods done to see if you are absorbing it? That would be the first thing to try. Make sure any bloods are done during your period, so your own E is lowest and you will most clearly see what you're getting from the HRT.

The problem is that most GPs will tell you that bloods of 250pmol are lovely and you should be very happy and any remaining symptoms are not due to hormones. But they are wrong. Many women - especially younger women - need higher doses of estrogen because a lot of the symptoms are due to fluctuations and the higher doses 'buffer' the fluctuations during perimenopause.

I'm with Newson Health and my Newson doctor says that many women need E between 400-600pmol during peri-menopause for symptom resolution. HRT isn't really designed to give this kind of dose, for most women it gives a much lower dose around 250-350pmol.

For me, I need a high dose of E (I'm on 9 pumps of gel and about to increase to 10 pumps/day) to get me to just 450pmol - because I don't absorb it well. Which is all to say, since you don't know which direction to go, a blood test could really help if you do it during your period. If it isn't at least 450, try an increase.

From my own experience, I noticed zero improvement in many of my symptoms until I passed the magic threshold of 8 pumps of gel. There wasn't a gradual improvement as I gradually increased - nothing seemed to be happening and i was very dubious that this was estrogen related and that anything was going to get any better. But I'd explored lower doses and they hadn't helped so exploring higher doses was all I had left to do really. Things weren't getting worse, so I kept going up. At 8 pumps things got dramatically better. Even slightly better still at 9 pumps, but I'm not totally symptom-free yet so will be trying 10 pumps. (If I need even higher I will need to go to Sandrena or patches.)

The foggy head could be a progesterone side effect - what are you doing in terms of progesterone? But that is a lot of prescription drugs you are on, there, and the side effects of several of those include brain fog. Pregabalin is something I was prescribed but refused to take after reading the side effects and how difficult it can be to get off. Do experiment with stuff and you will eventually find what works for you - but it can take a while, this is a slow process!
« Last Edit: April 16, 2024, 10:10:38 AM by joziel »
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mandamoo85

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Re: Increase? Or just anxiety? Please help me!
« Reply #4 on: April 16, 2024, 01:39:37 PM »

Thank you for your thorough response. I’ve had a blood test, will find out the E levels on Friday (as through a meno-clinic).
I’m on 100mg progesterone continuous.
I would love to be off all meds and just HRT but that’s not realistic.
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Smorzando

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Re: Increase? Or just anxiety? Please help me!
« Reply #5 on: April 16, 2024, 04:26:42 PM »

Please be aware that antidepressants can cause night sweats! I don’t know if that’s the case with you but it’s worth considering. I had the most awful night sweats on both Sertraline and higher doses of Venlafaxine - the sweats stopped completely on stopping the drugs. I was around your age at the time and in hindsight, not perimenopausal then. I’m now 49, certainly perimenopausal, and don’t get night sweats at all (although I do have a whole host of other fun symptoms!)

Just my perspective, in case it’s of use to anyone.
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Penguin

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Re: Increase? Or just anxiety? Please help me!
« Reply #6 on: April 16, 2024, 04:41:56 PM »

A temporary increase in citalopram caused excessive sweating for me, it was listed as a side effect. It stopped when I went back to lower dose.
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mandamoo85

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Re: Increase? Or just anxiety? Please help me!
« Reply #7 on: April 16, 2024, 07:13:09 PM »

Thanks guys. I know all meds can cause night sweats etc. that’s why I don’t know if I should be using HRT. 50mcg helped, I was more myself! Then it’s gone a bit wrong.
I would love to stop my meds, I’m just so sensitive and it’s a long drawn out process which, with 2 kids, is really difficult.
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