It's a highly personal thing. For example I used to have Estradot patches, but gel was promoted and recommended highly on here, so I thought I would give it a try and was given Sandrena. As Kathleen says it is thicker than estrogel but is also much stickier so takes a while to dry, (compared with estrogel which is quite runny like testogel - the formulation is the same apart from the active ingredient) but is more concentrated so you need less of it for the same dosage of estradiol.
However my flushes came back and because patches worked well ( lack of efficacy wasn't the reason for my changing to gel) and I didn't want to spend time trying to tweak the dosage when I could just go back to patches, so I did. After trying various different patches - not through choice but because of the shortages - when I was given different alternatives by the doc, and changed every time there was a shortage ( except for estraderm which I drew the line at!) - I was finally given Evorel and have stuck (!) with these even though I'm sure I coud get Estradot again - because I think they're really good and I'm sure I get more oestrogen from them.
So really, go for it with an open mind and see how you get on, is my advice!
All the best!
Hurdity x
