Hi annie79, sorry to hear you are struggling with this horrible problem, I too had a similar issue I was on 3 pumps of estrogel for 4 years started at 43 but it didn’t stop the awful vaginal ,vulva and bladder issues to develop , I also couldn’t go to 4 pumps as it caused unwanted side effects also can’t use patches due to reaction of glue, I started on vagifem but after months on it with everyday doses it just didn’t do anything for me although lots of women do really well on it , I use ovestin internally and externally, I also use yes vm in and out , I also use hydramol ointment (not cream) my gp told me ointments are better than creams as the contain less fillers to wash with and apply after a shower it took around a year of doing this to feel some what normal again, but I still get flare ups , so using the patch or gel doesn’t stop the dryness for me but for some it does , I guess it’s about finding what will work for us because we are all different and respond differently to medications , do you use any vaginal moisturisers ? It can really help and make a difference to the dryness xx