Marchlove I have just noticed that you mentioned PMDD higher up in the thread. I have PMDD and can’t find a progesterone in can tolerate even vaginally. I am currently on a high dose of estrogen, that I’m also not tolerating, so reducing. But my menopause symptoms are so severe that I don’t know how I’m going to manage. My ‘hot flushes’ are beyond anything my gp or gynae has seen before - both in intensity or length because it goes on for hours. I really hope this will help me but if you have any other suggestions like this they will be very gratefully received. Xx