Taz, it's hard to know with hormones. Since I'm 54, I think there's a high likelihood that my hormones are finally settling. I haven't had a period for over four cycles now. Generally speaking, when the hormones start to flatline, the symptoms do, as well. For me, I think that the main issue was high estrogen relative to progesterone, and it was the imbalance between these hormones that caused so many of the physical and mental symptoms. I'm so glad that I toughed it out, but to get here, I went through HELL, and that's not an exaggeration!