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Menopause Matters magazine ISSUE 82 out now. (Winter issue, November 2025)

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Author Topic: utrogestan  (Read 4673 times)

discogirl

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Re: utrogestan
« Reply #15 on: September 01, 2022, 06:49:19 AM »

Hi  Suziemc,

That's interesting to know.

Well what I've done, I didn't take my utrogestan last night I took it this morning to see how it goes and I will give it a week or two to let things settle down.

My sleep pattern is horrific at the moment and I really don't want anything upsetting it.

I'll let you know how I get on with taking it in the morning. I know marchlove takes it in the morning and it seems to work fine.

thanks for your help xx
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Hurdity

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Re: utrogestan
« Reply #16 on: September 01, 2022, 08:04:03 AM »

Hi discogirl

Do you take Utrogestan vaginally or orally?

The effect of utrogestan on sleep is not as straightforward as helping or hindering sleep - it is more nuanced than that, as well as responses being individual.

First vaginal delivery and oral delivery may well have different effects because there are a large number/greater concentration of metabolic by-products from oral intake which may cause sdie effects ( and may affect sleep) in some women.

Secondly, while it is indisputable that progesterone has a sedative effect, taking utrogestan (which results in larger amounts of the hormone/metabolic by-products getting into the system all at once than would occur naturally during the menstrual cycle - it is released from the ovaries in steady bursts whereas in HRT is is taken once or at the most twice per day) can both help and hinder sleep.  Many women, including me, sleep more deeply and heavily when on the Utro phase, but it also can have a disruptive effect on sleep due to 1) effect on bladder meaning night time waking to pee - this happens to me 2) vivid dreams causing disturbed sleep. I don't know if the dreaming is due to the bladder trying to wake you up, or an effect of the hormone and its metabolites, but this certainly happens to me.

Overall I tend to wake in the mornings anyway with a heavy head and more fatigued than usual, when taking progesterone but if you have been suffering from lack of sleep, this may be preferable?

If you are taking it orally and after a few weeks or cycles it is having negative effects - then try taking it vaginally and see if this makes a difference.

I always take mine at night because I take it vaginally and it would fall out by day - due to having had several children!!!

Hope this helps :)

Hurdity x
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sheila99

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Re: utrogestan
« Reply #17 on: September 01, 2022, 08:38:38 AM »

When it's used for ivf it's used 3 times a day, twice during the day and once before bed so presumably it's done it's job before it comes out. Unless the capsule itself would fall out.
Has anyone tried taking it twice a day and found any difference in side effects (specifically fatigue)?
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discogirl

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Re: utrogestan
« Reply #18 on: September 01, 2022, 03:06:40 PM »

Hi Hurdity

Thanks for that information, really, really helpful.

I take it orally and since I only started HRT properly last Thursday, I'm going to stick with orally for the moment to see how I get on.

I took it this morning instead of tonight.

Taking the utrogestan vaginally is something I would definately consider if I cannot tolerate it orally.

Interesting what you say about the metabolic by-products from taking it orally rather than vaginally.

I think I should have done more research into all of this before I went into HRT, however when I'm due for my 3 monthly review I will see how I have gotten on with this route first.

Apart from the having to pee more and the vivid dreams and fatigue in the morning, have you experienced anymore side effects from the vaginal route.
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Hurdity

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Re: utrogestan
« Reply #19 on: September 02, 2022, 09:33:24 AM »

Hi discogirl

I have never taken it orally so I have nothing to compare with - I've always been a nil-by-mouth HRT gal right from the start (2008).

I do get generally more fatigued during the prog phase, a bit head foggy aometimes more sometimes less, and which builds up over the course of the 12 days, and sometimes a migraine.

Still prefer to take it because it is bio-identical.....

Hurdity x
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discogirl

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Re: utrogestan
« Reply #20 on: September 02, 2022, 06:31:58 PM »

thats really so helpful. im getting such good advice.  This forum has really been a lifeline for me.

are the side effects less when you use prog vaginally.

i find the oral route makes me anxious and on edge

thanks so much xxx
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