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[OllyO07]

Hi, I've been on Evorel Sequi 50 for almost a year and was noticing a return of symptoms so my GP has moved me to Estraderm 75 patches and 5mg Provera daily. That was about 2 weeks ago but I'm bleeding pretty heavily now. Is that just a short term side affect as was under the impression bleeding should stop under this new regime? Thanks

[Floradora]

Any change in HRT regime, particularly an increase in estrogen, can cause irregular bleeding until things settle down and your body adjusts. I wouldn’t worry unduly at this stage as it’s only been a couple of weeks but if things persist I’d have a chat with your GP . It’s a big jump going straight from 50 to 75 , sometimes if you increase more gradually over a couple of weeks (by cutting a bit off the patch and working up to the full dose) you can minimise the bleeding problems while you adjust. X

[joziel]

As well as the increase in estrogen, you've also changed the progesterone there. So it's hard to know what's causing it. Because some progesterones work better than others - it's very variable dependent on the woman. If it doesn't settle down within 3 months, then you might need to increase or change your progesterone.