Hi Im new to the forum so have been having some difficulties in navigating around the forum. Im 3 years post menopausal (periods stopped by 48/49 yrs) During this time I had been having terrible fluctuating moodswings with feelings of utter despair and any kind of enjoyment in anything, not to mention poor sleep and a constant worrying, like what is the point anymore. I also then started to get frequent water infections, so I decided it was time to really 'fight' to get some sort of different help from my doctor(s) who had not been at all helpful in the three years I had been explaining these symptoms to them. After various telephone appts, Ive been on Vagifem 10mg for almost 3 months and did the 2 weeks everyday with no obvious problems, only slight pelvic pain. I then reduced 2 vagifems each week. I then also started taking Evorel Conti 50 about 6 weeks ago, 2 patches a week and have noticed over the last month I have been getting very stressed, anxious, emotional, having panicky periods and feeling very overwhelmed with things and unable to cope with many situations. This week Ive skipped a vagifem and now have only used my patch and so far feel much calmer then 4 days ago. Could I be having too much estrogen thus making me get this anxiety and sheer panick to the point, I thought I was completely loosing my mind? Any help would be much appreciated. Thanks and sorry for the long paragraph x