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[Flan747]

I’m the complete opposite I believe the gel dried way til quickly for it to absorb properly? Hopefully more people will jump into this thread as I don’t see a lot about Lenzetto but what I do read is all positive 🤞

[Spangle1512]

I’m the complete opposite I believe the gel dried way til quickly for it to absorb properly? Hopefully more people will jump into this thread as I don’t see a lot about Lenzetto but what I do read is all positive 🤞

It’s fascinating the way they work so differently for different people.

[PMDD]

I think that sounds like a good plan, I initially started at 2 per day but my main symptom of low oestrogen was palpitations, and they quickly came back so I did increase every couple of weeks until these stopped. When I first increase, i do feel jittery for a few days until this levels off, but then im fine, so dont worry if this happens xx

I have been on Lenzetto for a while now, and initially moved over from 75 patches.

To start with the dose equiv was stated to be one spray was equiv to a 50mcg patch, but no way is that true, and my consultant is finding the same with his other patients.

I am now settled on 4 sprays a day, 2 in the morning & 2 PM. For me this seems similar to when i was on the 75 patch, but may need to go slightly higher yet.

Thank you.  I think 75 patch is equivalent to 3 pumps of gel so perhaps I should stick to the 3 sprays for now and see what happens.  My specialist said start at 3 and go up to 4 if necessary.

[Flan747]

Yes Ella you sound very similar to me! I split my dose and PM feel ok but AM I just feel so dreadful, this of course could be too much I have no idea but I’ve stick with it until my appt so the specialist has something to work with? It appears I absorb way too quickly?

[Floo36]

I have been in touch with the manufacturer of all the transdermals and looked at studies and from my own experience over the last 2 1/2 years, I’m also at Newson.  Lenzetto is more like 1 pump of gel, Louise Newson also mentions it on one of her videos.  We all absorb differently too, if you are lucky you may absorb 100% or if you are like me none or 10% or you may absorb gel but not a patch.  It’s very much trial and error.  The only thing you can do is give it a go. 

[Flan747]

Thank you for that Floo! I like the idea of 3 sprays instead of 6 pumps which I fell I need more of anyway as I don’t absorb! Hoping Newson clinic can guide me in the right direction as I’m a bit lost with it all!

[Sazzle42115]

Hi Floo36
Are you having difficulties with absorbing gel/spray? Any tips?

[Spangle1512]

I have been in touch with the manufacturer of all the transdermals and looked at studies and from my own experience over the last 2 1/2 years, I’m also at Newson.  Lenzetto is more like 1 pump of gel, Louise Newson also mentions it on one of her videos.  We all absorb differently too, if you are lucky you may absorb 100% or if you are like me none or 10% or you may absorb gel but not a patch.  It’s very much trial and error.  The only thing you can do is give it a go.

That’s really helpful, thank uou.

[Lamplighter]

Hello ladies, can I ask a slightly off-topic question here?  I wonder how you find out that you absorb the gel too quickly, or conversely, aren't very good at absorbing at all?  Do you somehow just know, or do you do tests to find out?

Just asking as I wouldn't have a clue whether I absorb too quickly or not very well, and seeing as how I've just upped my dose to four pumps a day (and not really noticed much difference so far) I wonder if I could be having problems with absorption.

Thanks xxx

[Floo36]

Hi Sazzle, I do have an absorption problem with transdermals.  I ended up paying for a lot of private Estrogen tests to finally prove it because I’m peri the bloods always showed high but they were just fluctuations not my real reading, I finally got some low ones whilst on HRT.  I never had improvements just got worse not matter how much I used, I was up to 12 pumps gel, 6 sprays, 2 patches, no change it was like I had applied nothing but the bloods finally proved it but it took over 2 years and a lot of suffering.  The doctors at Newson have said on one of the videos that there can be a 10 fold difference in absorption between us.  I am an unusual case I’m told so don’t be put off by my experience. 

Transdermals are the safest option but for some of us taking oral Estrogen is the only other option and quality of life comes first for me. 

[Nas]

Floo which oral Oestrogen do you take please?
I don’t think I absorb transdermal too well either and have been told my MS that it so an option if I want to try.

[Floo36]

Body identical estradiol, I get either zumenon or Elleste solo.

[Sazzle42115]

Thanks Floo, I am experiencing no improvement with the gel or Lenzetto now on 4 sprays Lenzetto a day but doesn't seem to be doing anything....back to MS in 2 weeks..

[Lamplighter]

Hello me again, any chance of someone answering my question above?  Would be very useful for me to hear how you come to know that you do/don't absorb transdermal HRT. 

I gather from Floo's post that tests indicated low absorption, is that how everyone has worked it out?

Thanks

[Flan747]

Floo: I’ve had several readings around 300 over the last 2 years and have been advised to increase hence being on 6 pumps! No improvement continue to have such rubbish days! Reading came back this week at 1156, I’m hoping this is a fluctuation but I did panic and reduced to 5 yesterday and had the worst day I’ve had in a long time! Palpitations all day until bed time!
Lamplighter: I think it’s all trial and error and mine unfortunately is all error at the minute! My appt with MS is Thursday! I feel like I need to reset?