YES VM irritated my bladder but I'm ok with YES WB, what suits one doesn't always suit another. When I used to have bladder problems, including a bladder prolapse, I'dI place the Vagifem low down, just inside targeting the bladder wall, this worked. Sometimes the fillers in Vagifem can also irritate the vulva, especially when placed low, always wash in just plain water, I wash in Cetraben.