Thanks for the info on your Amour & testing timings, Anna. OK, so your bloods are done 24 hours since last dose of Armour, same situation as my testing. Where did you get the "25% higher previous day" figure for your T3? I'm not familiar with that calculation. If your T3 was still mid-range 24 hrs after taking any, I wonder whether that points to your either being able to produce a significant amount of T3 for yourself or there being proportionately too much for you in your current Armour dose, as I think we are both coming to suspect. As mentioned earlier, 24 hrs after my dose of T3 (tiny by comparison with yours btw, but as much as I feel I need), my bloods show T3 to be below bottom of ref range, due to its short half life. The amount of T3 & T4 I take are more or less in physiological proportion to that produced by someone with a healthy, intact thyroid. Not by calculation - I just found in recent years that that ratio of replacement T4:T3 works best for me. My endocrine meds are not perfect by any means, given T3's short half life & the fact my HRT is still a work in progress, but I think the thyroid replacement we've fine-tuned is about as good as it gets for me.
Yes, various minerals & vitamins are involved in T4->T3 conversion which is why I always urge caution when any members with a thyroid condition talk about supplementing.
Can I ask have you always been on NDT or did you swap after finding synthetic thyroid hormones inadequate? I'm interested as I tried Armour too, in desperation about 15 years ago but couldn't make it work for me.
Don't worry, I know from your previous comments you are knowledgeable about the makeup of Armour & the powerful nature of T3. I also respect your individual experience & feel that no-one knows our own bodies better than us. But over the 25+ years since thyroidectomy I've also found it frustrating that however well meaning, most doctors have little training in thyroid disorders, which puts the onus on us to learn as much as we can, be our own detectives & advocates. I think this is where exchanging experiences can sometimes help throw a little light on what's going on.
I am not too happy about the way my doctor deals with patients; only seeing them once every 12-18 months because she's overbooked, the appointment only lasts one hour which isn't much with so much to go through (three pages of lab results...). So, it's more or less about renewing my prescriptions and telling me to get in touch if I have any questions.
I have to say I wouldn't be happy with that either. I see my Endo roughly every 3 months with email contact between & instructions to get in touch at any time I need to. He is as experienced & senior as it gets & very well respected. Oversees all my endocrine care including HRT. I think it's invaluable having an expert take a holistic view in our situation. I feel fully involved in decisions too - he listens, is very kind & not heavy handed, so worth his weight in gold to me.
I think the best thing I can do as things stand is to find a supplement that lowers blood sugar levels and increases insulin sensitivity.
Ooh Anna, do please be careful. Your blood sugar issues are different to mine (mine often low - confirmed by bloods - which can be a pain too), but I agree important to try to normalise the situation, though I would be wary of supplementing without supervision. Especially given your homoeostasis is already compromised by being menopausal with a chronic thyroid disorder.
I have no experience of steroids/DHEA, so can't help there I'm afraid.
Surprised to hear the gynaes you saw would only prescribe oral oestrogen when as we know transdermal is generally considered the safest method. And that one wanted to prescribe oestrogen without progesterone for a woman with intact uterus is pretty shocking.
It's not just oral E that stimulates breast tissue btw. All forms of E, P & T have effects on the breasts. Utrogestan is currently considered the safest form of progesterone in terms of risk, but that doesn't mean it has no effect on breast tissue.
?I think I should decrease Armour and add some T4. Maybe some of my symptoms would clear up with lower levels of T3 and slightly higher levels of T4. it's also entirely possible that my recent night sweats have been caused by too much T3 and not low E and P levels...or possibly a combination of both.?
I don't know for sure Anna, but I think you could be onto something with the level of short-acting T3 in Armour being possibly more than you currently need & the background T4 maybe being insufficient.
It worries me that you feel you have to manage all this largely on your own, given the doctor overseeing your care is only available for one inadequate consultation a year. I think in your situation I would ask around & try to get to see a recommended Endocrinologist who will listen & has the time to work with you.
I have not given up hope my condition is reversible.
No, please don't lose hope - it should be manageable with the right sort of sympathetic & open-minded expert help. Just that menopause is a time when everything can feel beyond control. But that will improve the further you go through, in as much as flatlining sex hormones mean a more stable base to work on.
My heart goes out to you & I really hope you manage to get the specialist help you need to get to the bottom of it & feel really well. Do keep posting if there's any way any of us might be able to help & to let us know how you get on.

Wx