Please login or register.

Login with username, password and session length
Advanced search  

News:

Got a story to tell for the magazine? Get in touch with the editor!

media

Pages: 1 ... 21 22 [23] 24 25 ... 35

Author Topic: Is this the right place to discuss compounded hormones?  (Read 262553 times)

Mary G

  • Member
  • *
  • Posts: 2768
Re: Is this the right place to discuss compounded hormones?
« Reply #330 on: February 14, 2022, 07:10:49 PM »

Crispy, migraines can have some very strange symptoms which is why they often go undiagnosed for years.

I have silent migraines (fewer now luckily) which consist of an aura that lasts for about 30 minutes but no headache although I do feel rough for the next 72 hours.  They started at the onset of the menopause (I had a Mirena coil at the time) and are caused by spiking oestrogen which in turn is caused by synthetic progesterone, high doses of Utrogestan and generic menopausal hormone instability.  I did not suffer with them during my reproductive years when hormones are more stable.   

Migraines with headaches and no aura are usually caused by progesterone withdrawal (menstrual type migraines) but migraines can change over time and I was wondering if your nausea and dizziness might be a form of silent migraine?   

I used to take 25mg DHEA every day but I stopped a while ago because I can no longer tolerate high doses of oestrogen and DHEA definitely converted to oestrogen in my case.  Now that I am very post menopause, I have loose bowels and (to a lesser extent) migraines if I take high doses of oestrogen, it's like my body rejects it.

It's complicated but I need to have stable hormones to keep the migraines away so I can't risk taking any medication I can't control that has the ability to convert to oestrogen.

dangermouse has gastric migraines which are also caused by oestrogen spikes - please correct me if I'm wrong dangermouse!


Logged

Marchlove

  • Guest
Re: Is this the right place to discuss compounded hormones?
« Reply #331 on: February 15, 2022, 09:10:45 AM »

I stopped taking testosterone a couple of months ago because of the nausea.
I might reintroduce it once I’m more balanced on the lower doses of estrogen and progesterone.
I’m most certainly in a better place with the lower doses (post menopause) which I see many other members seem to benefit from. xx
Logged

dangermouse

  • Member
  • *
  • Posts: 1305
    • Powersonality
Re: Is this the right place to discuss compounded hormones?
« Reply #332 on: February 15, 2022, 10:54:30 AM »

Yes that is well remembered Mary, gastric migraines! I was shocked with the diagnosis (endocrinologist) as I had always assumed migraines were about pain and I never had that. She also thought I may have had them since puberty but that my combined pill kept them at bay, as had neurological symptoms in my pill free week from about age 35, including a strange feeling of disassociation.

The migraines later were extreme nausea, like sea sickness (which was misdiagnosed as vertigo), twitching all over my body, a subtle weakness down my left leg and arm that would last for days, a pressure feeling in my head that later felt bruised on the back, right of my head, tachycardia to about 125bpm at rest and lots of eye floaters making my vision more blurred. I also had eye movement and sound sensitivity where at best watching TV or being somewhere where lots of background movement made me feel sick, and at worst I had to ensure my eyes were aligned with a spot on the wall for the whole day to not bring on the nausea. Some lasted 3 days, some 10 days and sometimes I just had constant low grade symptoms. All of this was amplified by GPs and A&E docs convinced my symptoms were due to a dangerous stomach ulcer, even though I had to wait 6m for a scan (hence, why I have now purchased private health insurance!) and was being, literally, force fed proton pump inhibitors at very high dose along with vertigo meds that make migraines worse! Perimenopause was never considered as I was only 46  ::)

So my clinic (London Hormone) have always wanted me to deal with one hormone at a time, although that may just be for my imbalances. Unlike other clinics I've read about here, they don't just do one size fits all. Once you know what works, there is the option to have a combined cream, although using patches or oestrogel/Lenzetto is initially offered as it works out cheaper.

I think when oestrogen is surging high you can either overwhelm it with high dose oestrogen (similar to the combined pill) to ramp down our own volatile production or subdue it with high dose progesterone. The latter is preferred as it means you don't need to then monitor the womb lining.

This time around, I asked for a separate testosterone cream last autumn to try once my progesterone had calmed the volatility. The dose was 0.5ml to take 5 days of the week. It made me feel similar to the oestrogen so I didn't continue it. Although my clinic also prescribe DHEA, I had purchased one before online and that had made me feel migraine like, nothing extreme but I felt it was interfering with trying to settle with just the progesterone.

It may be the case, and I've certainly read it on this forum, that oestrogen levels need to be high before testosterone is no longer converted to oestrogen. Could be the same with DHEA.
Logged

CrispyChick

  • Member
  • *
  • Posts: 1749
Re: Is this the right place to discuss compounded hormones?
« Reply #333 on: February 15, 2022, 12:36:01 PM »

Oh my goodness. It's a total minefield.

So the migraines were caused by high estrogen Dangermouse??? Absolutely horrific. I'm not convinced that's my case as my symptoms are constant, from the moment I wake... Some days worse than others. I assume there was no cure for your 'migraines'???? Just attempts tobstsbakise your hormones?!

I'm feeling really dispondent today. I stopped the test/DHEA yesterday. Felt slightly better yesterday afternoon. Headache migraine in evening - put that down to stopping the hormones.

Today I feel as bad as ever.  :'(

So... This is it now. Next month up to 100mg cream. I'll stay off the test/dhea - at best it was making me calm, at worst it was making me worse. I've not noticed any difference from the DIM, so think I'll stick with that for the 30 days.

Something is making me feel this bad, every min of every day. I'm not even getting the little respite I used to get at times during second half of cycle. But on the whole my symptoms are just my usual, but at their absolute worst.

I note, whilst my mood is OK, I'm feeling easily teary this week (not massively). Now, i am feeling sorry for myself, but i also wonder if it's a low prog symptom as I'm in second half of cycle.

I'm so sick of feeling sick.  :(

My only hope is that ramping up the prog cream and stopping the test /dhea (they were combined) will take time and work eventually... But I need to remember they weren't the cause of my symptoms in the first place - so all focus is bowvon the prog cream and dim.  ???
Logged

dangermouse

  • Member
  • *
  • Posts: 1305
    • Powersonality
Re: Is this the right place to discuss compounded hormones?
« Reply #334 on: February 15, 2022, 02:54:46 PM »

As well as individual hormones potentially creating turmoil, the main source of turmoil is changing something, so you really need time to let things settle. It's no wonder you feel awful whenever you change something as your body needs time to adapt.

As you've been consistent with the test/DHEA that makes sense to remove it for now, as it hasn't settled for you, and just stuck with the prog and DIM. I would also not have any prog gaps, if you were doing withdrawal weeks, you want as much consistency as possible.

If you feel that the prog builds up (bloating or too sedated) then I would try taking it on alternate days which is better than taking a week off once a month. It take about 48 hours before you get prog withdrawal symptoms so that should stop it kicking in. You just want something consistent over the course of a few weeks to see if it's really suiting you. Then you test other doses and add other things in later if necessary.

Remember though that your own is oestrogen will be having its own volatile dance in the background. You could try noting down over the course of a month how you feel to see if there is a cyclical pattern going on behind. Then you are not disappointed when it repeats the following month and can be ready to ride it out.
« Last Edit: February 15, 2022, 02:57:31 PM by dangermouse »
Logged

CrispyChick

  • Member
  • *
  • Posts: 1749
Re: Is this the right place to discuss compounded hormones?
« Reply #335 on: February 15, 2022, 05:20:15 PM »

Thanks, Dangermouse.

You're absolutely right. Consistency is key. You did however open my eyes to the DHEA. I've read into it a bit now, and I don't think it's a trial I want to do, at this point in time. Like you say, I've given it a good bash - and I feel truely awful. So it's certainly been no help... I'm hoping now it has been a hinderence.

I was just reading an article about how DHEA (heralded as the hormone of youth) can work for done but be very bad for others. Think I'd rather concentrate on the mainstream hormones first.

I have experienced a big mood drop today. Perking up a bit now. Could well be the drop. If the DIM can give u bad headaches, I'm sure withdrawing test and dhea can do something.

I want to give the prog a really big last shot.  I'll try to get to the 100mg next week and stick. That's what MG instructed me to do.

The only way is up...  ;)

« Last Edit: February 15, 2022, 05:37:33 PM by CrispyChick »
Logged

Marchlove

  • Guest
Re: Is this the right place to discuss compounded hormones?
« Reply #336 on: February 15, 2022, 09:07:12 PM »

Keep going CrispyChick we’re all there for you!
Wise decision to concentrate on the Progesterone going forward.
Keep trucking! xx
Logged

CrispyChick

  • Member
  • *
  • Posts: 1749
Re: Is this the right place to discuss compounded hormones?
« Reply #337 on: February 16, 2022, 09:39:02 AM »

Thank you Marchlove  :-*

That's the DIM dropped today. Only made it to day 9, but yesterday was so bad (could've been a come down from the dhea/test) ... But I feel I need to strip everything out, bar the prog cream.

Apparently DIM once it's converted estrogen can recycle it making things worse... So another thing not to add in at the mo.

I am going to finish this months 50mg prog cream course tomorrow and take the break, as instructed by my MG doc. That way I'll know if I feel different on no prog cream. Then restart on 100mg...of which I'm nervous. Just can't really take much more of feeling so ill  :-\
Logged

HelloSam666

  • Guest
Re: Is this the right place to discuss compounded hormones?
« Reply #338 on: February 16, 2022, 10:30:26 AM »

It was interesting to read about the migraines and how we've all had different experiences.

Like Crispy Chick, i only thought there was one type so it was an education to hear about silent migraines and others.

Just for reference, I only started getting them in my mid 30s (severe pain, one side of head). Although i didn't have periods, being on the mini pill, the migraines were once a month for 2 days so i assumed that was aligned in some way to my periods. I finally went to see my GP who described them as hormonal migraines and prescribed Sumatriptan. When my peri-menopausal started last year, I had insomnia & migraines occurring most days. These migraines were far more debilitating than the insomnia and I was taking Sumatriptan pretty much every day. Even if i could catch them in time with Sumatriptan, they still left me feeling horribly unwell & wishing for bed time to come around fast. Days just wasted!

As i said before, trying Dim caused almighty migraines - worse than anything i've previously experienced.

Crispy Chick - i'm sure it was Mary G that suggested to me that it would be fine to continue the progesterone cream without a break. I have followed that advice and all fine & on an even keel. I can't remember now if you've already tried using the progesterone cream without a break? I know you're going to follow the procedure from your clinic for now & without anything else diluting the results, so see how that goes - i so hope you get a breakthrough. But worth thinking about - for me, a low dose of progesterone cream continuously is working.

In any case, it's good for us all to connect and see how we can help each other. The information i've received on this thread has been invaluable and what you're experiencing Crispy could so easily be an issue for any of us at a different time & visa versa.

Logged

CrispyChick

  • Member
  • *
  • Posts: 1749
Re: Is this the right place to discuss compounded hormones?
« Reply #339 on: February 16, 2022, 11:21:29 AM »

Thanks Sam

I'm actually keen to take the break this month... As I'm suspicious it's the prog cream making me feel this bad. I took it an hour later this morn... And swear I feel a lot worse after taking it. But...im also coming down from the DIM and DHEA/TEST... So too hard to say. But the break for a bleed will help work that out. After all, this is the first month I've taken it all month.

If it is the prog cream - it's most prob too low. I fully intend to go to the 100mg next week...  :o
Logged

HelloSam666

  • Guest
Re: Is this the right place to discuss compounded hormones?
« Reply #340 on: February 16, 2022, 11:28:45 AM »

I understand Crispy, we all know our own bodies well enough now to understand what might / might not be working. I think i might have missed your post about taking it all month. We'll see how it pans out next week with the change of dose and a clean slate from the other medication. Take care, Sam
Logged

dangermouse

  • Member
  • *
  • Posts: 1305
    • Powersonality
Re: Is this the right place to discuss compounded hormones?
« Reply #341 on: February 16, 2022, 12:05:28 PM »

Yes good luck CrispyC with what you're doing, I definitely found that too low dose prog made me worse, it seemed to
churn everything up. When I had higher oestrogen, so similar to your phase, I never found a perfect dose and it was more after stopping for a year and looking back I realised it had made me feel a lot better than I'd realised going by the year without it. I wish I had tried higher though as now it's lower the 100mg (50 was still too low) firmly stopped any oestrogen volatility.

Re the DIM, again at your phase I had an initial ramp up of overstimulation so I didn't give it a chance - I was always so petrified I'd be back on that 'boat' for the next couple of weeks. Now my oestrogen is very low but gently surging the DIM is coping with doing what it should be doing. Your testing makes me feel that the same may have happened to me back then.
Logged

Marchlove

  • Guest
Re: Is this the right place to discuss compounded hormones?
« Reply #342 on: February 16, 2022, 01:47:21 PM »

Hi Crispy
My meno lady says to always take the progesterone at night. At the moment I’m using a 25mg lozenge but about to increase to 50mg.
Don’t know if taking it at night might help things for you x
Logged

Mary G

  • Member
  • *
  • Posts: 2768
Re: Is this the right place to discuss compounded hormones?
« Reply #343 on: February 16, 2022, 08:15:54 PM »

I really hope you have some improvement soon Crispy but I do wonder if your ultimate solution will be continuous progesterone.

Marchlove, I'm glad you are getting on well with the lozenges and hope the mouth sensitivity has improved.

Logged

Marchlove

  • Guest
Re: Is this the right place to discuss compounded hormones?
« Reply #344 on: February 17, 2022, 09:02:46 AM »

Thank you for remembering Mary G. No it didn’t improve, so my specialist told me to swallow them for now which resolved the problem.
Bizarrely, I have no problem taking the Bi-est lozenges that way.
I remember reading somewhere that estrogen is good for oral health, so maybe that’s why. x
Logged
Pages: 1 ... 21 22 [23] 24 25 ... 35