Hey Sharon - just to throw into the conversation, I was on lisinopril for High Blood pressure and I had to get it changed, it started reacting with my hrt. It made my feet and ankles swell and I got a bit of strange rash on my legs. It was weird because I had been on the lisinopril for years! GP looks at me and goes "oh yes, that happens sometimes, its well known with Lisinipril!" and promptly changed the blood pressure meds to Lercandipine. Problem gone! Just in case anyone has the same problem x