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[Hurdity]

Good post from Stellajane - my regime is very similar but I use patches instead of gel.

You may be reacting initially to the drop in progesterone - ie withdrawal effects - which, if this is the case, will not last, and your body will acclimatise to the alternate day dosing. Are you using it vaginally? I can't imagine 100 mg oral use will be sufficient to protect the womb from oestrogenic stimulation by 2 pumps of gel - but as Stellajane says you would be able to determine this through regular scans to arrive at doses of each which eliminate your symptoms but protect the womb sufficiently.

Like Stellajane, I have only ever been on a cycle (apart from a brief few months on reduced dose of oestrogen - 25 mcg patch with vaginal Cyclogest every alternate day) and have never really had any problems at all. My flushes have never returned since I maintained the 50 mcg dose and I feel absolutely fine (if more tired than previously - but expect in my 60's!). If you steel yourself to put up with the bleed then hopefully it will work for you too. I can't comment on what it would be like if you are in the throes of peri-menopause though - as I started HRT when I was late peri.

I hope you get sorted soon

Hurdity x

[MicheleMaBelle]

Hi Hurdity- thanks. I'm at the stage now if I don't know if I'm coming or going. I have terrible brain fog. I'm taking the utrogestan vaginally . When I first went on HRT 18 months ago, I was still having periods so was put on sequential regime. When I went back earlier this year due to low mood etc, my GP changed me to cyclical and a different regime. Kliovance made me feel really bad as did Everol conti patches ( until I halved them) Flushes came back but I started to feel more like me for the first time in years. I just don't know what to do now.

[Peacegirl]

Peacegirl, , I also get the sore and engorged breasts on oral progesterone, as well as IBS symptoms. Will be interesting to see if your breasts also settle down on the vaginal route. I do not get the oversedation, just very vivid dreams. Please let us know :-)

Sore and hard with prickling around the nipples here lol!  I mean 'tender' doesn't actually cover it as it's been waking me up in the night, although better this morning, so I hope you're right 

[Peacegirl]

Hi ladies- a bit late to this thread. I e mailed my consultant last week as a month into my 2 pumps of oestrogel and 100mg of daily utrogestan, I was feeling pretty ropey and it's got a lot worse since I switched from sequential to cyclical therapy. So, I reckon like a lot of you, I'm struggling with the progesterone.

I see him again in June but in the meantime he's suggested that I can either switch to sequential therapy at standard 200 mg dose OR try 100 mg alternative days. I'm going for the second option and see how I get on but today I woke up with very sore joints so don't know if I should be upping the oestrogen dose- any idea? It scares me to increase it when I'm taking a smaller dose of Utrogestan. I'm only two days into the alternative day regime. Why is this so bloody difficult? 

That's odd because I've also been waking with sore joints and I wondered if the progesterone was knocking out the oestrogen (if that's even possible?) or perhaps I was do sedated I was sleeping too heavily on the daily 100mg utrogestan. Anyway I've put myself on 100mg alternate days vaginally and kept with the 2pumps and will see how this works. I can report that the horrible flu-like feeling has lifted. It is hard you're right. I'm feeling very grateful right now as my symptoms are minor compared to what they were. I would suggest going a bit longer with your new regime if you can-although this is not expert advice obviously! Also, are you rubbing the gel in effectively? My specialist said much could be lost through not rubbing it in well? I'm sure you'll get dime good advice on here soon.

[MicheleMaBelle]

Thanks Peacegirl- I'll rub it in some more! I had my 100mg of utrogestan last night and fell asleep ok. Woke up at 2.30am feeling totally wired and skin itching and burning. Didn't get back to sleep and am so tired today. Joints seem to be even more sore. I'm feeling really rubbish today- going on holiday soon but TBH can't get excited about  it as I feel so crap and don't want to spoil it for my husband.
I'm getting so fed up with this HRT malarkey that I really do feel like coming off it. Sorry for the moan- let me know how you get on as our regimes are very similar x

[Peacegirl]

Stellajane, if you have time, can you explain what you mean by '12 days of utrogestan every other month'? I'm wondering if I should try cyclical as I'm not worried about a bleed. I am worried though about getting oestrogen highs and the accompanying insomnia without progesterone. 

Michelemabelle, I really do empathise, it's awful being crap. The only think which helped me through was to have a little self-accpetance around not feeling 100%. Ive told my partner that if I feel rubbish when we go away next month he'll have to do his own thing and leAve me to sleep and read. Luckily he doesn't mind this x

[MicheleMaBelle]

Funny enough, my husband doesn't mind either...I wonder why?
I think StellaJane means that she does sequential HRT but the progesterone part is only taken every second month for 12 days, instead of monthly. So she'll have a month of combined therapy, oestrogen for the first part of the month and then progesterone for 12 days along with the oestrogen. next month its oestrogen only, following month, oestrogen and progesterone.

if we take 100 mg vaginally every second day, we're getting the equivalent of 1500 per month. Sequential therapy is normally 200 mg for 14 days so 2800 monthly. If SJ is taking 200 mg for 12 days every second month it's the equivalent of 1200 on a monthly basis ( I know it doesn't quite work like that but it's to try and give a comparison)
I'm seeing consultant in June- my worry is that by taking it every second day, what this will do to the womb thickness and balance of oestrogen. Hey ho, it's worth a try x

[Tracey E]

Hi, are any of you still on the Utrogestan every other day regime. It would be interesting to know if you percevered and the outcome. Thanks.

[juliemargaret]

Hi jenna....
I read your post with interest. How you feeling now?. Im.on alternate days utro.and daily estrogel. Only a week in. So.far ok..had a bleed but expected but been having mild headaxhes...hoping these go?! Im.peri meno....but my meno doc.who is an expert in jer field assired me alternative days vaginally is just fine !! Any thoughts?

[Jenna]

Sorry, juliemargaret, but you need to ask Smarlo and matildamouse - I only provided the link.