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[racjen]

Yes, I'm still on Evorel 100 patches with Utrogestan 100mg for 10 days a month. It's just really thrown me that the AD was helping, and then once I hit progesterone withdrawal I feel far worse again - I guess I was expecting that it wouldn't be so bad, but apart from anything else the AD meant I made it thru the whole 10 days of Utrogestan, which I've never managed before, so maybe the fall-out was always going to be worse. Weird thing is, I've had a bleed, finished a couple of days ago, and yet I still feel crap  . I think I'm going to go up to the higher dose of AD tonight - if my GP isn;t around till next Weds she can't expect me to just wait for permission.....

[GypsyRoseLee]

How are you today racjen?

Have you considered reducing down to doing 7 days of Utrogestan per month? This is how much I take and it's the right balance for me.

[racjen]

That's what I normally do GRL, mainly because I normally can't cope with more than 7 or 8 days. But this month it didn't affect me anything like so badly so I thought maybe the mirtazapine was somehow helping. Obviously a bad decision - despite having had a bleed several days ago I still feel really really depressed, have spent all morning in bed. Took the higher dose of AD last night but I guess that might make me feel worse for a few days too. Just whe I thought things might be starting to get better...

[CLKD]

I find that upping my AD as necessary for a few days really helps my brain.  It never makes me feel worse.

[racjen]

Normally when you start an AD they warn you that you may feel worse for the first few days, until your brain's got used to it. The same thing can happen when you up the dose. It may not happen to you, but it does happen to plenty of other people.

[CLKD]

Has it eased yet?

[racjen]

Has it eased yet?

No, still down in the pit 

[racjen]

Thanks Birdy, helps to know I'm not the only one. I so envy people who get depressed or anxious, go to the doctor, get given an AD, take it for a few weeks with minimal side effects and then feel fine. I seem to know quite a few - why can't I be one of them?

[CLKD]

That's something that needs investigating surely racjen  .   I had to try 5 B4 we found one that didn't make me really ill  and that did me well for 8 years. 

[racjen]

How do you think they'll investigate it CLKD? In my experience of anxiety and depression it's just trial and error - they keep trying you on different ADs util they either hit on one that you're OK with, or you give up. And lots of other women on here are having the same experience. I don't know what you think they can do, because scientific knowledge of the idiosyncracies of the brain is still so sketchy,and we're all so different in our reactions - brain scans perhaps (that's a joke by the way?) You say yourself it took 5 tries before you found one that worked for you - were you asking for investigation after the first few didn't work? If it were that straightforward there wouldn't be so may women on this board suffering for months/years on end would there?

[Tc]

Racjen. I am waiting to see if I can get wellbutrin. Instead of working on seratonine reuptake it works on dopamine reuptake.
I read about it and asked my phych if I could take it last time he suggested I go back onto ADs.

My physch said he wants to check with a colleague first as it's off license here so I wont know until next visit if I can get it. (He gave me escitalopram in meantime which I havent started.)
I wondered if it might interest you as it works in a different way to most SSRIS..

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