Hi, I have had mild IBS for around 25 years now, but it has definitely got worse in the last few years. I have IBS D and these past two summers have been awful. For some reason it is worse when it is hot. Also I had to have a course of anti biotics last year and that really made things worse still.
Have you tried the low Fodmap diet? Lots of info around on it. I have started to take silicole gel, which tastes disgusting but does keep my stomach calm. And since I started taking it, only a week or so ago, I haven't had so many trips to the loo. And I have been able to have a slightly more varied diet.
I also have downloaded the headspace meditation app which has helped me stay calmer, which of course means less stress on my stomach.
I am just turned 54 and still have periods regularly, and my stomach does play up even more around period time. It always has done. But seems extra sensitive due to peri. I don't take HRT, because my father had a DVT around my age, and I am very wary of it happening to me.
I recently had blood tests for thyroids, hormone levels, b12 etc they all came back fine. The doctor said i am not even in peri! But at 54 with night sweats, insomnia and some anxiety issues, I know I am.