Hi Ivery been having problems absorbing estradot have gone from 37.5 to 150mcg. When I apply the patch it feels within about 2 hours that my levels are rising then by 3rd day it feels like it has worn off and need next one. I've been doing it every 3 days but feels like a roller coaster. I changed from buttock to thigh advised by consultant. I have an appointment in 2 weeks to get bloods redone. I'm just wondering if this is the pattern people have had when problems absorbing. I've been keeping a diary and only finding a few hours out of the 3 days I feel ok