I have tried it twice, the first time it made me suicidal, that was maybe 15 years ago. I tried again about 2012 and it made my tinnitus worse (quinine is known to do that) even taking only 2 doses per week so it gave up again.
What I would say is build up very slowly, maybe twice a week at first and so on. Don't let them tell you you need to go mad at the beginning it can take at least 3 months for you to feel the benefits and there is nothing to be gained from rushing as it often has bad tummy side effects, but many people I know with lupus etc swear by it once it gets to work.