Ok, five weeks on.....used Sandrena every day for a little under 3 weeks, now only on mon, wed, fri. Flushes and night sweats completely gone, VA gone.....no itching or soreness, anxiety levels massively reduced, sleeping almost normal. So, how much better do I feel? I'd say around 95% it's amazing how 1.5mg of Sandrena per week is enough for me to have such a huge difference to my wellbeing. Now the negative......as I'm away on a six week trip I didn't want to take progesterone as no way did I want a bleed whilst away!! So NO progesterone.......but what to do when back home? Haven't bled for over 6 years. Previously took progesterone on the 3 days with the gel, never had a bleed or any problems but that was my own "made up" regime. Just concerned as to what's happening with lining of womb!!